Reactivity of routine HIV antibody tests in children with perinatally acquired HIV-1 in England: cross-sectional analysis
26 Apr, 2019
Authors: Fidler KJ, Foster C, Lim EJ, et al.; for Collaborative HIV Paediatric Study (CHIPS) Steering Committee Published in: Pediatr Infect Dis J. 2019;38(2):146-148 Abstract We assessed HIV antibody prevalence in children with perinatally acquired HIV in England. Eighteen percent (10/55) of…
Read MoreAccelerated aging in perinatally HIV-infected children: clinical manifestations and pathogenetic mechanisms
26 Apr, 2019
Authors: Chiappini E, Bianconi M, Dalzini A, et al. Published in: Antimicrob Resist Infect Control. 2019;8:13 Background Premature aging and related diseases have been documented in HIV-infected adults. Data are now…
Read MoreAdult dolutegravir 50mg film-coated tablets in children living with HIV weighing 20 to <25 kg
14 Apr, 2019
Authors: Bollen P, Turkova A, Mujuru H, et al. for the ODYSSEY Trial Team Published in: 26th Conference on Retroviruses and Opportunistic Infections, March 4th – 7th, 2019– Seattle. P_830
Read MoreTime to viral suppression in perinatally HIV-infected infants depends on the state of HIV disease progression at start of ART
30 Mar, 2019
Authors: Schröter J. Published: Oral presentation at 26th International HIV Dynamics & Evolution, March 24th-27th, 2019, Cascais, PT
Read MoreNucleoside reverse transcriptase inhibitor backbones and pregnancy outcomes
26 Mar, 2019
Authors: European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) Study Group Published in: Aids. 2019;33(2):295-304. Objectives The aim of this study was to investigate whether specific nucleoside reverse transcriptase inhibitor (NRTI) backbones are…
Read MoreBirth Defects After Exposure to Efavirenz-Based Antiretroviral Therapy at Conception/First Trimester of Pregnancy A Multicohort Analysis
26 Mar, 2019
Authors: Martinez de Tejada B; European Pregnancy and Paediatric HIV Cohort Collaboration Study Group. Published in: J Acquir Immune Defic Syndr. 2019;80(3):316-324 Background To investigate the association between efavirenz (EFV)…
Read MorePredictors of faster virological suppression in early treated infants with perinatal HIV from Europe and Thailand
25 Mar, 2019
Authors: Chan MK, Goodall R, Judd A, et al. Published in: Aids. 2019; 33(7):1155-1165 Objective To identify predictors of faster time to virological suppression among infants starting combination antiretroviral therapy (cART) early in infancy. Design Cohort study of…
Read MorePaediatric European Network for Treatment of AIDS (PENTA) guidelines for treatment of paediatric HIV-1 infection 2015: optimizing health in preparation for adult life
31 Dec, 2018
Authors: Bamford A, Turkova A, Lyall H, et al.; for PENTA Steering Committee Published in: HIV Med. 2018;19(1):e1-e42. Abstract The 2015 Paediatric European Network for Treatment of AIDS (PENTA) guidelines provide practical…
Read MoreHIV specific B-cell memory persists in seronegative early treated children and is dominated by IgM-memory responses
31 Dec, 2018
Authors: Cotugno N, Morrocchi E, Pepponi I, et al. Published in: J Immunol. 2018; 200 (1 ) 182.34; Abstract Early initiation of ART in HIV vertically infected infants influences specific immunity…
Read MoreHigh rates of prescribing antimicrobials for prophylaxis in children and neonates: results from the antibiotic resistance and prescribing in European children point prevalence survey
26 Dec, 2018
Authors: Hufnagel M, Versporten A, Bielicki J, et al.; for ARPEC Project Group. Published in: J Pediatric Infect Dis Soc. 2018. doi: 10.1093/jpids/piy019. Background This study was conducted to assess the variation…
Read MoreThe impact of clinical pathways on antibiotic prescribing for acute otitis media and pharyngitis in the emergency department
26 Dec, 2018
Authors: Dona D, Baraldi M, Brigadoi G, et al. Published in: Pediatr Infect Dis J. 2018;37(9):901-907. Background Although Italian pediatric antimicrobial prescription rates are among the highest in Europe, little action has…
Read MoreThe epidemiology of adolescents living with perinatally acquired HIV: a cross-region global cohort analysis
26 Dec, 2018
Authors: Collaborative Initiative for Paediatric HIV Education and Research (CHIPER) Global Cohort Collaboration Published in: PLoS Med. 2018;15(3):e1002514. Background Globally, the population of adolescents living with perinatally acquired HIV (APHs) continues…
Read MorePathways of care for HIV infected children in Beira, Mozambique: pre-post intervention study to assess impact of task shifting
26 Dec, 2018
Authors: Marotta C, Giaquinto C, Di Gennaro F, et al. Published in: BMC Public Health. 2018;18(1):703. Background In 2013, Mozambique implemented task-shifting (TS) from clinical officers to maternal and child nurses to…
Read MoreOptimizing clinical trial design to maximize evidence generation in paediatric HIV
26 Dec, 2018
Authors: Ford D, Turner R, Turkova A, et al. Published in: J Acquir Immune Defic Syndr. 2018;78(1):S40-S48. Abstract For HIV-infected children, formulation development, pharmacokinetic (PK) data, and evaluation of early toxicity are critical…
Read More”Treatment is not yet necessary”: delays in seeking access to HIV treatment in Uganda and Zimbabwe
26 Dec, 2018
Authors: Kawuma R, Seeley J, Mupambireyi Z, Cowan F, Bernays S; for REALITY Trial Team Published in: Afr J AIDS Res. 2018;17(3):217-225 Abstract We examined the logic that individuals use to account for delaying HIV testing…
Read MoreEconomic evaluation of weekends-off antiretroviral therapy for young people in 11 countries
26 Dec, 2018
Authors: Tierrablanca LE, Ochalek J, Ford D, et al; for BREATHER (PENTA 16) Trial Group Published in: Medicine (Baltimore). 2018;97(5):e9698 Objectives To analyze the cost effectiveness of short-cycle therapy (SCT), where patients take…
Read MoreWeekends-off efavirenz -based antiretroviral therapy in HIV infected children, adolescents and young adults (BREATHER): extended follow-up results of a randomised, open-label, non-inferiority trial
26 Dec, 2018
Authors: Turkova A, Moore CL, Butler K, et al. for BREATHER (PENTA 16) Trial Group. Published in: PLos One. 2018;13(4):e0196239. Background Weekends off antiretroviral therapy (ART) may help engage HIV-1-infected young people facing…
Read MoreLate identification of Chikungunya virus in the central nervous system of a 2-month-old Infant: persistence of maternal-neonatal infection?
09 Dec, 2018
Authors: Di Maio Ferreira FCPA, da Silva ASV, Bispo de Filippis AM, Brasil P Published in: J Pediatric Infect Dis Soc. 2019 Jan 18 Abstract We report here a probable…
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