Apr, 2018

SMILE: enrollment has resumed

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We are pleased to announce that enrollment in the SMILE study has recommenced. 3 new participants have recently been recruited in the clinical trial: 2 in Porto, Portugal and 1 in Zurich, Switzerland.

SMILE is a multicentre randomised study evaluating safety and antiviral effect of a once daily integrase inhibitor administered with Darunavir/Ritonavir compared to standard of care among HIV-1 infected, virologically suppressed paediatric participants.

PENTA is sponsor of this study, with 300 children due to be enrolled from about 30 sites from 10 countries.


Feb, 2018

PREPARE response to seasonal influenza in Europe – a press release from the PREPARE project

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The EU funded project PREPARE has released a communication brief updating stakeholders on the project activities related to this season’s influenza activity.

press release has also been published with more information about the exciting and innovative PREPARE’s ALIC4E clinical trial. This is the only study that is currently randomizing patients to receive antiviral treatment or not. This study will answer the question about whether Oseltamivir is clinically and/or cost effective or not when treating primary care patients with influenza-like illness.

PENTA is partner in PREPARE (Platform for European Preparedness Against (Re-)emerging Epidemics) project, an EU funded network for harmonised large-scale clinical research studies on infectious diseases, prepared to rapidly respond to any severe ID outbreak, providing real-time evidence for clinical management of patients and for informing public health responses.

To know more about the project, visit the PREPARE website.