News

25

May, 2022

Penta-ID Network Meeting (PIM) 2022

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The Penta ID Network Meeting 2022 (PIM, 28-30 April 2022) gave our members – the Penta family – a great opportunity to meet face-to-face, after more than two years of distance due to the COVID-19 pandemic. The beautiful Sorrento in Italy set the stage for three days of talks, discussions, debates, and social activities (including a visit to nearby Pompei and a historical restaurant in the city). Over the years, PIM has strengthened the connections between collaborating institutions, industries, and international organizations associated with the Penta ID Network. These connections have helped […]

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20

May, 2022

Youth engagement and participation in clinical trials

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Involving patients in our clinical trials is of utmost importance to us. Penta is dedicated to ensuring that the young people in our trials are included at various stages of the research process. In late April 2022, Mercy Shibemba, one of our PPI experts, sat down with two members of our Youth Trials Board (YTB) to talk about the work that they do and what it’s like to participate in clinical trials as young people living with HIV.   What do you do as part of the Youth Trials Board? [...]
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19

May, 2022

Penta at the Global Child Health Mini-Symposium in Oxford April 7th 2022

 

Penta was highly represented at the Mini-Symposium hosted by Green Templeton College – University of Oxford on the 7th of April 2022 entitled “Serving the children of the world: examining the current research needs in Paediatrics”. The key idea of the symposium was exploring the needs of child health globally and acknowledging the importance of facilitating research collaboration in global health. The topics of the symposium spanned from Perinatal Medicine to Adolescent Health. World class speakers from all over the world as well as students from Oxford, contributed towards making […]

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18

May, 2022

Penta investigates cases of acute hepatitis of unknown origin in children

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On 12 May, a Rapid Communication on the reported increase of acute hepatitis of unknown origin in children was published in Eurosurveillance. The paper outlines the extent and geographical distribution of these unexplained paediatric hepatitis cases in Europe and beyond. It also highlights the challenges of drawing comparisons against a baseline of a syndrome which is not under systematic surveillance and has no standard case definitions in place. Acute hepatitis of unknown origin is a rare paediatric syndrome, which causes severe inflammation of the liver and may require transplantation. Lately, […]

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18

May, 2022

RBDCOV initiates the first Phase III clinical trial of HIPRA’s Covid-19 vaccine in immunocompromised people

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One of the objective of RBDCOV is to test whether the vaccine can reactivate or re-generate a protective immune response against the virus The RBDCOV project, in which Penta is a partner, started a Phase III clinical trial of the Covid-19 vaccine in immunocompromised people, after the Spanish Agency for Medicines and Health Products (AEMPS) authorised it on 9 May. This clinical trial will determine whether an additional dose of HIPRA’s Covid-19 vaccine can generate an immune response in people living with immune system disorders, such as immunodeficiencies or who […]

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16

May, 2022

Capacitating the future of research in paediatric HIV

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By design, capacity building is a fundamental part of the UNIVERSAL project. The aim of the project's capacity building activities are to improve the ability of African and European young investigators in designing and conducting clinical trials. As such, the project conducted a Training Needs Assessment (TNA) from March 17th to June 21st 2021 among 108 African early career researchers from Cameroon, Mali, Senegal, Uganda and Zimbabwe who are involved in the project (see fig 1 below). A TNA is the process of collecting and analysing data to determine what [...]
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11

May, 2022

The EPIICAL story

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In 2016 the Early-treated Perinatally HIV-infected individuals: Improving Children’s Actual Life (EPIICAL) consortium began gathering scientists and clinicians specialising in paediatric HIV to work towards establishing new, scientific efforts on the early treatment of HIV to improve the lives of children and ultimately lead to the remission of HIV in children. The main focus of the consortium was the development of a predictive platform to inform treatment strategies that would lead to HIV remission. EPIICAL 2016-2020 succeeded in designing and conducting studies on paediatric HIV which led to the development […]

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26

Apr, 2022

GARDP study reveals that babies are increasingly dying of neonatal sepsis caused by drug-resistant bacterial infections

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Geneva, 26 April 2022 – A large study focusing on newborn babies with clinically diagnosed sepsis has revealed the impact of antibiotic resistance on neonatal sepsis, a major cause of death in newborns. At the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), the Global Antibiotic Research and Development Partnership (GARDP) has released a second wave of findings from its study on the outcomes of more than 3,200 newborns with neonatal sepsis, a life-threatening bloodstream infection that affects up to 3 million babies a year. The study shows that […]

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26

Apr, 2022

GARDP study reveals that babies are increasingly dying of neonatal sepsis caused by drug-resistant bacterial infections

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Geneva, 26 April 2022 – A large study focusing on newborn babies with clinically diagnosed sepsis has revealed the impact of antibiotic resistance on neonatal sepsis, a major cause of death in newborns. At the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), the Global Antibiotic Research and Development Partnership (GARDP) has released a second wave of findings from its study on the outcomes of more than 3,200 newborns with neonatal sepsis, a life-threatening bloodstream infection that affects up to 3 million babies a year. The study shows that […]

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