Towards understanding global patterns of antimicrobial use and resistance in neonatal sepsis: insights from the NeoAMR network
16 Oct, 2019
Authors: Li G, Bielicki JA, Ahmed ASMNU, et al. Published in: Arch Dis Child.2091;0:1-6 Objective To gain an understanding of the variation in available resources and clinical practices between neonatal units (NNUs) in the low-income and…
Read MoreDifferential susceptibility of Staphylococcus epidermidis biofilms to vancomycin, daptomycin and linezolid between clinical Isolates from neonates and adults
15 Oct, 2019
Authors:Simitsopoulou M, Kadiltzoglou P, Kyrpitzi D, Roilides E. Published in: Int J Biol Med Res.2019;10(1):6591-6596 Abstract This study aimed to compare the effects of vancomycin, linezolid and daptomycin against planktonic…
Read MorePopulation pharmacokinetic meta-analysis of individual data to design the first randomized efficacy trial of vancomycin in neonates and young infants
14 Oct, 2019
Authors: Jacqz-Aigrain E, Leroux S, Thomson AH, et al. Published in: J Antimicrob Ther 2019; 74(8):2128-2138
Read MoreUse of the WHO Access, Watch, and Reserve classification to define patterns of hospital antibiotic use (AWaRe): an analysis of paediatric survey data from 56 countries.
18 Jun, 2019
Authors: Hsia Y, Lee BR, Versporten A, et al; GARPEC and Global-PPS networks. Published in: Lancet Glob Health. 2019;7(7):e861-e871 Background Improving the quality of hospital antibiotic use is a major goal of WHO’s global…
Read MoreHard to study, hard to treat: putting children at the centre of antibiotic research and development
05 Jun, 2019
Authors: Balasegaram M, Pécoul B, Gray G, Sharland M, Swaminathan S. Published in: Lancet Infect Dis. 2019;19(6):573-574 Abstract Newborn babies, infants, and children are substantially affected by antimicrobial resistance. Globally,…
Read MoreR&D for children’s antibiotics – a wake-up call
28 May, 2019
Authors: O’Brien S, Sharland M, Zaoutis T Published in: AMR CONTROL 2019-2020; online edition Abstract It is time to prioritize children’s needs in the context of antimicrobial resistance (AMR). Children,…
Read MoreThe use of polymyxins to treat carbapenem resistant infections in neonates and children
26 Apr, 2019
Authors: Thomas R, Velaphi S, Ellis S, et al. Published in: Expert Opin Pharmacother. 2019;20(4):415-422. Introduction The incidence of healthcare-associated multidrug resistant bacterial infections, particularly due to carbapenem resistant organisms, has been on the rise…
Read MoreEffects of an antimicrobial stewardship intervention on perioperative antibiotic prophylaxis in pediatrics
26 Apr, 2019
Authors: Donà D, Luise D, La Pergola E, et al. Published in: Antimicrob Resist Infect Control. 2019;8:13. Purpose This study aims to determine the effectiveness of anAntimicrobial Stewardship Program based on a…
Read MoreHigh rates of prescribing antimicrobials for prophylaxis in children and neonates: results from the antibiotic resistance and prescribing in European children point prevalence survey
26 Dec, 2018
Authors: Hufnagel M, Versporten A, Bielicki J, et al.; for ARPEC Project Group. Published in: J Pediatric Infect Dis Soc. 2018. doi: 10.1093/jpids/piy019. Background This study was conducted to assess the variation…
Read MoreThe impact of clinical pathways on antibiotic prescribing for acute otitis media and pharyngitis in the emergency department
26 Dec, 2018
Authors: Dona D, Baraldi M, Brigadoi G, et al. Published in: Pediatr Infect Dis J. 2018;37(9):901-907. Background Although Italian pediatric antimicrobial prescription rates are among the highest in Europe, little action has…
Read MorePlasma and CSF pharmacokinetics of meropenem in neonates and young infants : results from the NeoMero studies
26 Apr, 2018
Authors: Germovesk E, Lutsar I, Kipepr K, et al.; for NeoMero Consortium Published in: J Antimicrob Chemother. 2018;73(7):1908-1916 Background Sepsis and bacterial meningitis are major causes of mortality and morbidity in…
Read MoreSurveillance for control of antimicrobial resistance
26 Apr, 2018
Authors: Tacconelli E, Sifakis F, Harbarth S, et al; for EPI-Net COMBACTE-MAGNET Group Published in: Lancet Infect Dis. 2018;18(3):e99-e106. Abstract Antimicrobial resistance poses a growing threat to public health and the provision of…
Read MoreEffects of clinical pathway implementation on antibiotic prescription for pediatric community-acquired pneumonia
26 Apr, 2018
Authors: Donà D, Zingarella S, Gastaldi A, et al. Published in: PLoS One. 2018;13(2):e0193581. Background Italian pediatric antimicrobial prescription rates are among the highest in Europe. As a first step in…
Read MorePharmacodynamics of vancomycin for CoNS infection: experimental basis for optimal use of vancomycin in neonates
15 Dec, 2016
Authors: Ramos-Martin R , Johnson A, Livermore J, et al. Published in: J Antimicrob Ther 2016;71(4):992-1002
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