Predictors of faster virological suppression in early treated infants with perinatal HIV from Europe and Thailand
25 Mar, 2019
Authors: Chan MK, Goodall R, Judd A, et al. Published in: Aids. 2019; 33(7):1155-1165 Objective To identify predictors of faster time to virological suppression among infants starting combination antiretroviral therapy (cART) early in infancy. Design Cohort study of…
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HIV specific B-cell memory persists in seronegative early treated children and is dominated by IgM-memory responses
31 Dec, 2018
Authors: Cotugno N, Morrocchi E, Pepponi I, et al. Published in: J Immunol. 2018; 200 (1 ) 182.34; Abstract Early initiation of ART in HIV vertically infected infants influences specific immunity…
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Time of ART initiation in perinatally HIV-infected children impacts on HIV-specific T cell functionality
02 Sep, 2018
Authors: Rinaldi S, Cotugno N, Pallikkuth S, Pahwa R, Palma P, Pahwa S Published in: J Immunol. 2018; 200(1):166 Abstract Early initiation of antiretroviral therapy (ART) in vertically HIV-infected children…
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Time to viral rebound after stopping art in children treated from infancy in cher
02 Sep, 2018
Authors: Violari A, Chan M, Otwombe KN, Panchia R, Jean-Philippe P, Gibb D, Cotton M, Babiker A Published: Oral presentation at 25th Conference on Retroviruses and Opportunistic Infections, March 4th…
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Lasting immune impacts of age at start of ART in vertically HIV-infected adolescents
02 Sep, 2018
Authors: Cameron M, Rinaldi S, Richardson B, Cotugno N, Williams S, Pallikkuth S, de Armas LR, Cameron C, Pahwa R, Palma P, Pahwa S Published: 25th Conference on Retroviruses and…
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Factors associated with HIV DNA levels in children starting antiretroviral therapy (ART) early in infancy
02 Sep, 2018
Authors: Chan M, Tagarro A, Zangari P, Ferns B, Foster C, De Rossi A, Nastouli E, Ángeles Muñoz-Fernández M, Gibb D, Rossi P, Giaquinto C, Babiker A , Palma P,…
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Human Immunodeficiency Virus (HIV) – Antibody Repertoire Estimates Reservoir Size and Time of Antiretroviral Therapy Initiation in Virally Suppressed Perinatally HIV-Infected Children
28 Aug, 2018
Authors: Rocca S, Zangari P, Cotugno N, et al. Published in: J Pediatric Infect Dis Soc.2018; 28. doi:10 Background Assays to estimate human immunodeficiency virus (HIV) reservoir size require large amounts of blood,…
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HIV specific IgM memory B-cells dominate in seronegative early-treated children
02 Aug, 2018
Authors: Cotugno N, Morrocchi E, Pepponi I, Rocca S, Cameron M, Rinaldi S, Di Cesare S, Pallikkuth S, Bernardi S, Klein N, Ananworanich J, Rossi P, Pahwa S, Palma P…
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Early and highly suppressive ART are main factors associated with low viral reservoir in European perinatally HIV infected children
26 Jun, 2018
Authors: Tagarro A, Chan M, Zangari P, et al; on behalf of the EPIICAL Consortium Published in: J Acquir Immune Defic Syndr. 2018;79(2):269-276 Background Future strategies aiming to achieve HIV-1 remission are likely to target…
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Report from the First EPIICAL General Assembly meeting, 9–11 November 2017, Rome, Italy
22 Jan, 2018
Authors: Zangari P, Palma P, Cotugno N, et al. Published in: J Virus Erad.2018;4: 51–54 Abstract: The first EPIICAL General Assembly meeting was held in an atmosphere of growing optimism. Many novel and exciting proposals for…
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Impact of time of ART initiation on HIV specific T cell functionality in perinatally infected young adults
31 Dec, 2017
Authors: Rinaldi S, Cotugno N, Pallikkuth S, Palma P, Pahwa S; on behalf of the EPIICAL Consortium Published: 8th Conference on HIV Persistence Background Early initiation of antiretroviral therapy (ART) in…
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Factors associated with time to virological response in children with perinatal HIV in Europe and Thailand initiating antiretroviral theraphy (ART) very early in infancy
02 Sep, 2017
Authors: Palma P, Chan M, Goodall R, Judd A, Gibb D, Babiker A, Rojo P. Published: 35th Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID), May 23rd-27th…
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B-cell responses in early treated long term viral suppressed seroneg HIV infected children
02 Sep, 2017
Authors: Palma P, Zangari P, Cotugno N, Rocca S, Nastouli E, McCoy LE, Ferns RB, Pahwa S, Rossi P Published: 24th Conference on Retroviruses and Opportunistic Infections, February 13th –…
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Early antiretroviral therapy in children perinatally infected with HIV: a unique opportunity to implement immunotherapeutic approaches to prolong viral remission
14 Jul, 2015
Authors: Klein N, Palma P, Luzuriaga K, et al. Published in: Lancet Infect Dis. 2015;15(9):1108-1114 Abstract From the use of antiretroviral therapy to prevent mother-to-child transmission to the possibility of HIV cure hinted at by…
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The EPIICAL project: an emerging global collaboration to investigate immunotherapeutic strategies in HIV-infected children
30 Jun, 2015
Authors: Palma P, Foster C, Rojo P, et al. Published in: J Virus Erad. 2015;1(3):134-139. Abstract The EPIICAL (Early-treated Perinatally HIV-infected Individuals: Improving Children’s Actual Life with Novel Immunotherapeutic Strategies) project arises from the…
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