Human Immunodeficiency Virus (HIV) – Antibody Repertoire Estimates Reservoir Size and Time of Antiretroviral Therapy Initiation in Virally Suppressed Perinatally HIV-Infected Children

28 Aug, 2018

Authors: Rocca S, Zangari P, Cotugno N, et al. Published in: J Pediatric Infect Dis Soc.2018; 28. doi:10 Background Assays to estimate human immunodeficiency virus (HIV) reservoir size require large amounts of blood,…
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HIV specific IgM memory B-cells dominate in seronegative early-treated children

02 Aug, 2018

Authors: Cotugno N, Morrocchi E, Pepponi I, Rocca S, Cameron M, Rinaldi S, Di Cesare S, Pallikkuth S, Bernardi S, Klein N, Ananworanich J, Rossi P, Pahwa S, Palma P…
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Early and highly suppressive ART are main factors associated with low viral reservoir in European perinatally HIV infected children

26 Jun, 2018

Authors: Tagarro A, Chan M, Zangari P, et al; on behalf of the EPIICAL Consortium Published in: J Acquir Immune Defic Syndr. 2018;79(2):269-276 Background Future strategies aiming to achieve HIV-1 remission are likely to target…
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Report from the First EPIICAL General Assembly meeting, 9–11 November 2017, Rome, Italy

22 Jan, 2018

Authors: Zangari P, Palma P, Cotugno N, et al. Published in: J Virus Erad.2018;4: 51–54 Abstract: The first EPIICAL General Assembly meeting was held in an atmosphere of growing optimism. Many novel and exciting proposals for…
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Impact of time of ART initiation on HIV specific T cell functionality in perinatally infected young adults

31 Dec, 2017

Authors: Rinaldi S, Cotugno N, Pallikkuth S, Palma P, Pahwa S; on behalf of the EPIICAL Consortium Published: 8th Conference on HIV Persistence Background Early initiation of antiretroviral therapy (ART) in…
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Factors associated with time to virological response in children with perinatal HIV in Europe and Thailand initiating antiretroviral theraphy (ART) very early in infancy

02 Sep, 2017

Authors: Palma P, Chan M, Goodall R, Judd A, Gibb D, Babiker A, Rojo P. Published: 35th Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID), May 23rd-27th…
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B-cell responses in early treated long term viral suppressed seroneg HIV infected children

02 Sep, 2017

Authors: Palma P, Zangari P, Cotugno N, Rocca S, Nastouli E, McCoy LE, Ferns RB, Pahwa S, Rossi P Published: 24th Conference on Retroviruses and Opportunistic Infections, February 13th –…
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Early antiretroviral therapy in children perinatally infected with HIV: a unique opportunity to implement immunotherapeutic approaches to prolong viral remission

14 Jul, 2015

Authors: Klein N, Palma P, Luzuriaga K, et al. Published in: Lancet Infect Dis. 2015;15(9):1108-1114 Abstract From the use of antiretroviral therapy to prevent mother-to-child transmission to the possibility of HIV cure hinted at by…
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The EPIICAL project: an emerging global collaboration to investigate immunotherapeutic strategies in HIV-infected children

30 Jun, 2015

Authors: Palma P, Foster C, Rojo P, et al. Published in: J Virus Erad. 2015;1(3):134-139. Abstract The EPIICAL (Early-treated Perinatally HIV-infected Individuals: Improving Children’s Actual Life with Novel Immunotherapeutic Strategies) project arises from the…
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