Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: the PENTA 5 randomised trial
18 Apr, 2002
Authors: Paediatric European Network for Treatment of AIDS (PENTA) Published in: Lancet.2002;359(9308):733-740 Introduction Treatment options for children with HIV-1 are limited. We aimed to compare activity and safety of three…
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Difficulties in achieving suppression of viral replication in vertically HIV-1 infected infants early treated with d4T+ddI+NFV : The PENTA 7 Study.
18 Feb, 2002
Authors: Compagnucci A, Saidi Y, Chaix ML, et al. Published in: 9th Conference on Retroviruses and Opportunistic Infections February 24-28, 2002 – Seattle. Poster 809 – W.
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TREC Response to Antiretroviral Therapy in HIV-infected Children in the PENTA 5 Trial
18 Feb, 2002
Authors: De Rossi A, Klein N, Walker AS, De Forni D, Babiker A, King D, Gibb DM for the PENTA Group. Published in: 9th Conference on Retroviruses and Opportunistic Infections,…
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The Impact of HIV-1 Subtypes on Virological Response and Emergence of Resistance in the PENTA 5 Trial
18 Feb, 2002
Authors: Pillay D, Gibb DM, Walker AS, De Rossi A, Kaye S, Ait-Khaled M, Muñoz-Fernandez M, Babiker A for the PENTA Group. Published in: 9th Conference on Retroviruses and Opportunistic Infections,…
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Pharmacokinetics (PK) of Nelfinavir (NFV) and its Active Metabolite (M8) in Very Young Infants Infected with Human Immunodeficiency Virus (HIV)
18 Apr, 2001
Authors: Litalien C, Faye A, Compagnucci A, Jacqz-Aigrain E. Published in: Pediatric Academic Societies 2001 Annual Meeting, April 28th – May 1st 2001, Baltimore MD. Abstract 2609.
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Evolution of drug resistance in antiretroviral therapy-naïve children in PENTA 5
18 Apr, 2001
Authors: Loveday. C., Walker. A.S., Gibb. D.M., on behalf of the PENTA virology Group Published in: Fifth International Workshop on HIV Drug Resistance and Treatment Strategies, 2001, Scottsdale, USA. Abstract …
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T cell repopulation in HIV infected children on highly active anti-retroviral therapy (HAART)
18 Apr, 2001
Authors: King D J.S., Gotch F M., Larsson-Sciard E. Published in: Clin Exp Immunol.2001;125(3):447-454 Abstract In this pilot study, we address the nature of the re-population of the T-cell compartment…
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Evaluation of Toxicity, Tolerability and Antiviral Activity of Early d4T+ddI+Nelfinavir (NFV) Therapy in HIV-1 Vertically Infected Infants : 24 Week Preliminary Results from the PENTA 7 Study
18 Feb, 2001
Authors: Faye A , Compagnucci A., Saidi Y; for the PENTA 7 Executive Committee Published in: 8th Conference on Retroviruses and Opportunistic Infections, February 4th-8th, 2001, Chicago. Poster 678
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Nelfinavir doses should be increased in infants less than 3 months
18 Jul, 2000
Authors: Litalien C. Giaquinto C. Faye A. Mechinaud F. Grosch I. Compagnucci A. Jacqz-Aigrain E. Published in: XIII International AIDS Conference July 9th-14th 2000, Durban, South Africa. Abstract Mo PEB 2213…
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Reconstitution of the T-cell Pool in Treated, HIV-infected Children
18 Apr, 2000
Authors: King D, Gibb DM, Gotch F, Larsson-Sciard E. Published in: 7th Conference on Retroviruses and Opportunistic Infections, January 30th- February 2nd, 2000, Abstract 322., San Francisco. Abstract 322
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Immune repopulation after HAART in previously untreated HIV-1 infected children
18 Apr, 2000
Authors: Gibb DM, Newberry A, Klein N, de Rossi A, Grosch-Wörner I, Babiker A Published in: Lancet.2000; 355: 1331-2 Abstract In 25 vertically HIV-infected children receiving highly-active antiretroviral therapy, a…
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A randomised trial evaluating three NRTI regimens with and without Nelfinavir in HIV-infected children: 48 week follow-up from the PENTA 5 trial
18 Apr, 2000
Authors: Gibb. D. M. for the PENTA 5 Executive and the PENTA Steering Committee. Published in: Oral presentation at 5th International Congress on Drug Therapy in HIV Infection, Glasgow 22-26 October 2000 also published…
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Drug resistance in a trial of nucleoside analogue and protease inhibitor therapy in children (PENTA 5)
18 Apr, 2000
Authors: Kaye S. on behalf of the PENTA Virology Committee. Published in: 5th International Congress on Drug Therapy in HIV Infection, October 22nd-26th 2000, Glasgow. P_308.
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Parents’ attitudes to their HIV-infected children being enrolled into a placebo-controlled trial: the PENTA 1 trial. Paediatric European Network for Treatment of AIDS
01 Oct, 1999
Authors: Paediatric European Network for Treatment of AIDS (PENTA) Published in: HIV Med. 1999;1(1):25-31 Objective The study aimed to explore the experience of parents/care-givers to their child’s participation in a European randomized trial of immediate…
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Plasma viral load and genotypic resistance patterns in children adding lamivudine to current reverse transcriptase inhibitor therapy (PENTA 4 Trial)
18 Apr, 1998
Authors: Kaye S, Loveday C, Gibb DM., Newberry A. Published in: 4th International Congress, November 8ht-12th 1998, Glasgow. P_305
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A randomized double-blind trial of the addition of lamivudine or matching placebo to current nucleoside analogue reverse transcriptase inhibitor therapy in HIV-infected children: the PENTA-4 trial
12 Apr, 1998
Authors: Aboulker JP, Babiker A, Carrière I, et al. Published in: AIDS.1998;12(14):F151-F160 Objective To evaluate the toxicity, tolerability and effect on laboratory markers of adding lamivudine (3TC) to nucleoside analogue…
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HIV-1 viral load and CD4 cell count in untreated children with vertically acquired asymptomatic or mild disease. Paediatric European Network for Treatment of AIDS (PENTA)
05 Mar, 1998
Authors: Paediatric European Network for Treatment of AIDS (PENTA) Published in: AIDS. 1998;12(4):F1-8 Background Plasma HIV-1 RNA levels are high in vertically infected infants. Information in older children is limited, particularly in those who have not received…
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The safety and tolerability of zidovudine (ZDV) and zalcitabine (ddC) in children with symptomatic HIV infection – PENTA 3
18 Oct, 1997
Authors: Gibb DM, Carrière I, Giaquinto C, Martinez M for PENTA Published in: VIth European Conference on Clinical Aspects and Treatment of HIV-Infection, 1997, October 1st-15th, Hamburg, Germany
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