Severity and outcomes of Dengue in hospitalized children from five hospitals in Jamaica during the 2018-2019 epidemic: is this due to antibody dependent immune enhancement from ZIKA virus exposure?
25 Feb, 2020
Authors: Lue A. Published in: Oral presentation at 3rd international Conference on Zika Virus and aedes related infections, February 13th – 16th, 2020– Washington DC, USA.
Read MoreEarly ART-treated perinatally HIV-infected seronegative children demonstrate distinct long-term persistence of HIV-specific T and B cell memory
19 Feb, 2020
Authors: Cotugno N, Morrocchi E, Rinaldi S, et al; EPIICAL Consortium. Published in: AIDS. 2020 Feb 3. Objective To investigate long-term persistence of HIV-specific lymphocyte immunity in perinatally HIV-infected children treated within…
Read MoreImpact of early antiretroviral therapy initiation on HIV-specific CD4 and CD8 T cell function in perinatally infected children
19 Feb, 2020
Authors: Rinaldi S, Pallikkuth S, Cameron M, et al. Published in: J Immunol. 2020 Feb 1;204:540-549 Abstract Early initiation of antiretroviral therapy (ART) in vertically HIV-infected children limits the size…
Read MoreEtiology and outcome of Candidemia in neonates and children in Europe: an 11-year multinational retrospective study
11 Feb, 2020
Authors: Warris A, Pana ZD, Oletto A, et al. EUROCANDY study group. Published in: Pediatr Infect Dis J. 2020;39(2):114-120 Background Data on Candida bloodstream infections in pediatric patients in Europe…
Read MoreReturn of the founder Chikungunya virus to its place of introduction into Brazil is revealed by genomic characterization of exanthematic disease cases
14 Jan, 2020
Authors: Pereira Gusmão Maia Z, Mota Pereira F, do Carmo Said RF, et al. Published in: Emerg Microbes Infect. 2020;9(1):53-57 Abstract Between June 2017 and August 2018, several municipalities located…
Read MoreImplementation and impact of pediatric antimicrobial stewardship programs: a systematic scoping review
10 Jan, 2020
Authors: Donà D, Barbieri E, Daverio M, Lundin R, Giaquinto C, Zaoutis T, Sharland M Published in: Antimicrob Resist Infect Control.2020;9:3 Background Antibiotics are the most common medicines prescribed to…
Read MorePD-1+ CD4 T cells are associated with HIV reservoir size and impaired function of T follicular helper cells in children and young adults on long-term viral control
30 Dec, 2019
Authors: S. Rinaldi, V. Dinh, S. Pallikkuth, L. De Armas, R. Pahwa, N. Cotugno, E. Nastouli, C. Foster, P. Palma, S. Pahwa Published in: Poster presented at 9th International Workshop…
Read MoreStandardising neonatal and pediatric anitibiotic clinical trial design and conduct: the PENTA-ID network review
30 Dec, 2019
Authors: Folgori L, Lutsar I, Standing JF, et al. Published in: BMJ Open. 2019; 9:e032592 Abstract: Antimicrobial development for children remains challenging due to multiple barriers to conducting randomised clinical…
Read MoreRole of Magnetic Resonance Imaging and cranial ultrasonography in congenital Cytomegalovirus infection
12 Dec, 2019
Authors: Blazquez-Gamero D, Soriano-Ramos M, Martinez de Aragon A, et al. Published in: Pediatr Infect Dis J. 2019;38(11):1131-1137
Read MoreModulated Zika virus NS1 conjugate offers advantages for accurate detection of Zika virus specific antibody in double antigen binding and Ig capture enzyme immunoassays
30 Nov, 2019
Authors: Tedder RS, Dicks S, Ijaz S, et al. Published in: PLoS One. 2019;14(8):e0215708 Abstract: The accurate diagnosis and seroprevalence investigations of Zika virus (ZKV) infections remain complex due to…
Read MoreAnalysing small groups within clinical trials, while borrowing information from larger groups
14 Nov, 2019
Authors: Turner B, Ford D, Moore C, Gibb D, Turkova A, White I, and ODYSSEY trial team Published in: Oral Presentation atInternational Society for Clinical Biostatics; July 16th 2019
Read MoreYellow Fever virus reemergence and spread in southeast Brazil, 2016-2019
14 Nov, 2019
Authors: Giovannetti M, de Mendonca MCL, Fonseca V, et al. Published in: J Virol. 2019;94(1). pii: e01623-19 Abstract The recent reemergence of yellow fever virus (YFV) in Brazil has raised…
Read MoreFactors predicting the severity of dengue in patients with warning signs in Rio de Janeiro, Brazil (1986–2012)
14 Nov, 2019
Authors: Goncalves BS, Nogueira RMR, Bispo de Filippis AM, Horta MAP Published in: Trans R Soc Trop Med Hyg. 2019;113(11):670-677 Background Since 1981, >12 million cases of dengue have been…
Read MoreReduced time to suppression among neonates with HIV initiating antiretroviral therapy within 7 days of age
14 Nov, 2019
Authors: Domínguez-Rodríguez S, Tagarro A. Palma P, et al. Published in: JAIDS 2019;82(5):483-490 Abstract There are limited data on infants with HIV starting antiretroviral therapy (ART) in the neonatal period. We investigated the association…
Read MoreTime to HIV suppression in perinatally infected infants depends on the viral load and CD4 T-cell percentage at the start of treatment
12 Nov, 2019
Authors: Schröter J. Published in: Poster presented at 4th Workshop on Virus Dynamics, October 21st-23rd, 2019 -Paris, FR
Read MoreTowards understanding global patterns of antimicrobial use and resistance in neonatal sepsis: insights from the NeoAMR network
16 Oct, 2019
Authors: Li G, Bielicki JA, Ahmed ASMNU, et al. Published in: Arch Dis Child.2091;0:1-6 Objective To gain an understanding of the variation in available resources and clinical practices between neonatal units (NNUs) in the low-income and…
Read MoreDifferential susceptibility of Staphylococcus epidermidis biofilms to vancomycin, daptomycin and linezolid between clinical Isolates from neonates and adults
15 Oct, 2019
Authors:Simitsopoulou M, Kadiltzoglou P, Kyrpitzi D, Roilides E. Published in: Int J Biol Med Res.2019;10(1):6591-6596 Abstract This study aimed to compare the effects of vancomycin, linezolid and daptomycin against planktonic…
Read MorePopulation pharmacokinetic meta-analysis of individual data to design the first randomized efficacy trial of vancomycin in neonates and young infants
14 Oct, 2019
Authors: Jacqz-Aigrain E, Leroux S, Thomson AH, et al. Published in: J Antimicrob Ther 2019; 74(8):2128-2138
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