Children hospitalized for coronavirus disease 2019 (COVID-19): a multicenter retrospective descriptive study
We read with interest the article by Dr. Song R and colleagues in the Journal of Infection titled “Clinical and epidemiological features of COVID-19 family clusters in Beijing, China.”, published online in April 2020. The authors presented the epidemiological and clinical features of the clusters of four families and found that SARS-CoV-2 is transmitted quickly in the form of family clusters. Children in the families generally showed milder symptoms. As of April 28, 2020, the coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been responsible for more than 3.05 million confirmed cases around the world. Early evidence showed that children seemed to be escaping the worst effects of the SARS-Cov2. However, a recent study indicated children with SARS-CoV-2 infection could be detected in early January 2020 in Wuhan. Another study reported that children are as susceptible to COVID-19 as adults. As the number of children infected with COVID-19 gradually increases, the disease has been documented in infants, children and adolescents, however, limited reports analyzed pediatric patients with COVID-19. Although a recent review has summarized the clinical features and management of infected children,5 the spectrum of disease of children outside Wuhan are still limited. Therefore, we included 46 children (≤18 years of age) hospitalized with positive real-time fluorescence polymerase chain reaction (RT-PCR) results of throat swabs were included from four tertiary-care hospitals in Guangdong, Hunan, and Hubei Provinces, China between January 20, 2020 and March 9, 2020.
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