Severe neutropenia in infants with severe acute respiratory syndrome caused by the novel coronavirus 2019 infection
Infection with severe acute respiratory syndrome caused by the novel coronavirus 2019 (SARS-CoV-2) and resulting coronavirus disease 2019 (COVID-19) is a global pandemic. Pediatric cases have some peculiarities, such as milder clinical manifestations and different laboratory abnormalities. A systematic review on laboratory data identified 12 articles, with a total of 66 pediatric patients. Lymphopenia was found in only 3% of children, whereas lymphopenia often is described in adult patients. Neutropenia was recorded in 6% of cases, but it was never less than 0.500 x 109 /L in this population.
We describe a 23-day-old and a 39-day-old infant with mild COVID-19 and severe neutropenia who were cared for at our tertiary care referral pediatric hospital.
Read the full case report here.