At the Penta Foundation we are continuing to work remotely during the national lockdown that has been introduced by the Italian government. Throughout this time, we have been able to continue our work from our homes, by utilising technology and ways to stay connected with our work colleagues; initiating video conferencing meetings and using instant messaging so we are able to brainstorm, share ideas and work together.
The lockdown restrictions in Italy are due to be eased over the coming weeks, and we will begin to use a mixed-model of remote and office based working, allowing us greater flexibility to continue our work, collaborate and ensure that we are keeping ourselves and others safe.
As you will be aware, the COVID-19 pandemic is affecting people and health services around the world, and in light of this rapidly evolving situation, Penta has asked its study teams to implement a number of amendments to Penta sponsored trials with immediate effect. These measures recognise the need for health professionals at each site to prioritise the support to COVID-19 affected patients during this emergency.
Our primary concern is the safety of all study participants and minimising any additional strain on our clinical sites and staff. Therefore, we are working closely with our clinical sites and partner organisations to find ways of doing this, and specific trial recommendations will be developed within each trial team in conjunction with the Sponsor. If you have any questions about what this means for your study then please contact the relevant trial team.
We will continue to keep you up-to-date on our activities throughout this period. We wish you all to remain safe and well during this time.
Find out here how Penta is committed to support research on COVID-19 pandemic
Penta is contributing to important collective global efforts in gathering real-time evidence for clinical management of patients affected by novel coronavirus (COVID-19), and for informing public health responses.
Together with our partners in PREPARE network and COMBACTE project, we have mobilized our network of paediatric clinical experts and collaborating sites in Europe and encouraged them to use the PREPARE-endorsed data collection tool for any children with possible novel coronavirus infections under their care. This tool is an electronic case report form (eCRF) that has been developed by ISARIC and WHO, in order to ensure the collection of standardised clinical data on patients hospitalised with suspected or confirmed infection with SARS-CoV-2. The data collected will be used for combined analysis to facilitate disease characterisation and inform clinical management and control.
To read more about the COVID-19 eCRF, visit the ISARIC website.
The PREPARE network, of which Penta is the paediatric gateway, has mobilised to Outbreak Research Response Mode 3, the highest response mode, which foresees the implementation of clinical research projects to address the most important and urgent clinical research questions posed by specific infectious diseases outbreaks. As a result of this action, PREPARE and its partners have pulled together a project proposal within the Horizon 2020 research framework, which was successfully selected for funding. Launched on March 10th, the RECOVER project aims to develop data and evidence-based knowledge on the SARS-CoV-2 epidemic, and translate these into recommendations for improved patient management and public health response measures.
Part of RECOVER project is the Hospital Care Study, aimed at analyzing the perceptions on infection control procedures for COVID-19 and the wellbeing of healthcare workers providing routine clinical care in the framework of a pandemic. Are you a healthcare-professional working in hospitals settings? RECOVER would love to know more about your experience with COVID-19 procedures. This is an anonymous survey: outcome will be used to inform European policy makers and advisors to set up interventions for protecting and supporting healthcare workers and preventing the spread of COVID-19.
Complete the survey!