WE-ARE-A-GLOBAL-MRN

We are a Global
Paediatric Research Network

devoted to determining and implementing the best ways
to prevent, diagnose and treat diseases in children

LINKING-EXPERTS-FROM-AROUND-THE-WORLD

Linking experts from
around the world

in an independent global collaboration that seeks to standardize
best practices across disease areas and populations

SHARING-VALUES-AND-GOALS

Sharing Values and Goals

such as flexibility, commitment and transparency

RESEARCHING-THE-RIGHT-DRUG-AND-THE-RIGHT-DOSE

Researching the right drug
and the right dose

to generate the scientific data necessary to market drugs
at doses that are safe and effective for children

UNDERSTNDING-THE-IMMUNE-RESPONSE

Understanding the
Immune Response

so as to harness the body's response
to HIV and antiretrovirals

FIGHTING-ANTIMICROBIAL-RESISTANCE

Fighting
Antimicrobial Resistance

to ensure effective treatments are available
for common infections for generations to come

PAVING-THE-WAY-FOR-WOMEN

Paving the way for women,
children and their families

to make powerful informed decisions about their health
and healthcare and improve the quality of their lives

LATEST NEWS

Penta at CROI 2020

6 March, 2020 - 2:56:35

The annual Conference on Retroviruses and Opportunistic Infections (CROI) will be held from March 8 to 11 in Boston, Massachusetts. CROI brings together top basic, translational, and clinical researchers from around the world to share the latest studies, important developments, and best research methods in the ongoing battle against HIV/AIDS and related infectious diseases.READ MORE

Penta at 10th International Workshop on HIV & Women

4 March, 2020 - 9:15:05

The 10th International Workshop on HIV & Women is in Boston on 6 – 7 March 2020, just prior to CROI. This is an outstanding opportunity for health care providers, researchers, government, industry and community representatives to discuss, debate, and increase their knowledge on HIV and its burden on women. READ MORE

PREPARE activated to Mode 3

3 March, 2020 - 4:41:53

The EU-funded Platform foR European Preparedness Against (Re-) emerging Epidemics (PREPARE) has decided to upgrade its response efforts to the COVID-19 epidemic to Outbreak Research Response Mode 3, the Clinical research mode. This is a direct result of the steep rise of confirmed cases of the virus in patients across Europe and the world. A…READ MORE

New publications from EPIICAL Consortium

19 February, 2020 - 3:57:07

Just published – data on T & B cell memory and T cell function in early-treated children in the Journal of Immunology and AIDS. Antiretroviral treatment (if started at an early stage) is able to reduce the amount of HIV virus in a child’s body. EPIICAL is studying the characteristics of the immune response and the amount of…READ MORE

GET TO KNOW US

Through independent research into child health operating on global scale, Penta is one of the most prominent scientific organizations dedicated to children’s health.

We are a non-profit Foundation with a remarkable expertise in coordinating projects, optimizing their financial and administrative management, disseminating scientific results and delivering training programs. The Foundation is sponsor of clinical trials according to the GCP guidelines and new relevant European Directives. We have recently entered into a number of framework collaboration agreements with world-leading paediatric research institutions.

We are an operational network, that brings together key stakeholders in paediatric infectious disease, including researchers, clinicians, regulatory bodies, the pharmaceutical industry and patients and their families, to plan and carry out high quality clinical research and training.

The network was established in 1991 as a collaboration between paediatric HIV centres in Europe. The primary aim of the network was to undertake independent clinical trials to address questions about antiretroviral therapies in HIV infected children, where answers could not be extrapolated from trials in adults. In 2011 the Penta network officially evolved into PENTA-ID (Infectious Diseases), extending its research to other paediatric infectious diseases. As such, we have been involved in several non HIV-related projects: where the main research focus is on adults, Penta represents a gateway for paediatric expertise thanks to its very well established network of paediatric hospitals. The Network now spans over 100 clinical sites in 28 countries, providing the access to paediatric patients necessary to perform clinical research.

In addition to coordinating and participating in trials and cohort studies, the Network develops treatment guidelines and training programmes for health care professionals thus contributing to European and global efforts to improve research infrastructure and harmonize and streamline research methods.

Currently the Penta Foundation and its network are involved in research projects in various developing countries that operate along 5 main lines of intervention: HIV and other viruses, Antimicrobials, Paediatric Medicines and Training.

In 2016 a spin off company (Penta ID Innovation) was set up by the Foundation in order to provide services to companies and invest directly in specific projects.

We look forward to building on our existing partnerships and seeking out potential new collaborations. Together, we are continually striving to improve the quality of life of children and their families.

Keep up to date with the latest Penta news

CURRENT PENTA STUDIES AROUND THE WORLD

ALWAYS EXPANDING

The Penta ID Network continues to grow, bringing together patients and their care-givers worldwide to address a wide range of healthcare issues.

110

CLINICAL SITES

31

COUNTRIES

29

YEARS OF ACTIVITY

24

EU FUNDED PROJECTS

PARTNERSHIPS

Founded in 1950, Doctors with Africa CUAMM is now Italy's leading non-governmental organisation working to protect and improve the wellbeing and health of vulnerable communities in Sub-Saharan Africa.
The Global Antibiotic Research & Development Partnership (GARDP) is a not-for-profit R&D organization that addresses global public health needs by developing and delivering new or improved antibiotic treatments, while endeavouring to ensure their sustainable access.
The INSERM-SC10 clinical trials unit was created to enhance the cooperative effort between clinicians and biologists involved in HIV therapeutic trials and to develop this endeavour on a European scale.
The MRC Clinical Trials Unit at UCL is at the forefront of resolving internationally important questions in infections and cancer, and delivering swifter and more effective translation of scientific research into patient benefits.
PHPT is an international collaborative research programme between the Faculty of Associated Medical Sciences at Chiang Mai University in Thailand, and the Institut de recherche pour le développement (IRD) in France. Its overall goal is to help improve HIV prevention and care at the family level through clinical research.