Penta Newsletter

News from our community and beyond

Every month we provide our subscribers with some of the latest news about our projects and studies and how we are working to ensure that medicines and vaccines are made available for children in the right dose, formulation and at the right time.

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Recent issues


World AIDS Day: Overcoming disruption, transforming the AIDS response

This World AIDS Day, we embrace UNAIDS’s call to overcome disruption and transform the AIDS response. Global health has faced unprecedented challenges like funding cuts, political uncertainty and fragile health systems, that threaten decades of progress against HIV. Yet disruption can also drive innovation. For Penta, this theme is both a challenge and an opportunity: to adapt, strengthen and ensure that our work continues to deliver impact for children and families worldwide.

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October 2025: Penta/EACS HIV treatment guidelines now available

Last month, a Penta delegation traveled to Paris for the European AIDS Conference (EACS) to present the paediatric section of the updated Penta/EACS HIV Treatment Guidelines 2025. These guidelines, which incorporate the Penta HIV recommendations published since 2009, undergo major revisions every two years to provide clinicians with the most up-to-date, evidence-based recommendations for treating newborns, children and adolescents living with HIV. This year’s edition brings some important updates, including a brand-new section on handling the transition from paediatric to adult care.

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September 2025

This month, we spotlight two projects that reflect our mission in action. PediSEP-1 introduces a risk-differentiated strategy to reduce unnecessary antibiotic use and limit AMR transmission in hospitalised children, supporting more precise, child-centred care in Africa. The THAI-CARES RSV Study has completed recruitment at eight sites in Thailand, moving closer to evaluating remdesivir as a treatment for paediatric RSV, a virus that hits children under five the hardest, causing over 3 million hospitalisations and 120,000 deaths annually.

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