News

Following closely on the publication of the PregInPoxVac children’s protocol, the PregInPoxVac maternal protocol paper has now been published in BMJ Open.

New results from the D3 (PENTA-21) trial, sponsored by Fondazione Penta ETS, add to the evidence that dolutegravir-based treatment remains a strong option for children living with HIV,

Every year, millions of children are admitted to hospitals with severe pneumonia, mostly in resource-limited settings. Until now, standard international guidelines have required children to stay in the hospital for…

Fondazione Penta ETS and the Medicines Patent Pool (MPP) have signed a Memorandum of Understanding (MoU), formalising a strategic collaboration to support the development and equitable access of priority health…

A protocol paper describing part of the PregInPoxVac study has been published in Vaccine. The paper outlines the design of a phase 3 trial evaluating the safety and immunogenicity of…

We’re pleased to share that a large delegation of Penta experts is heading to Rio de Janeiro, Brazil at the end of the month, taking part in three major events…

Uganda continues to face a high HIV burden among children and adolescents, with an estimated 71,000 young people aged under 15 years living with HIV and 3,100 AIDS-related deaths in…

Fondazione Penta is pleased to be part of a new international clinical development programme led by Enanta Pharmaceuticals, a clinical-stage biotechnology company, to advance zelicapavir, a new oral antiviral in…

About the author My name is José Sumbana, a young African investigator and Postdoctoral Fellow with a background in Microbiology, Biotechnology, and Life Sciences.

Every winter, hospitals around the world fill with infants struggling to breathe because of respiratory syncytial virus (RSV). Estimates show that RSV infects nearly every child by the time they…

We are pleased to share that Penta’s 2025 Annual Report is now available on our website. For more than thirty years, Penta has worked to ensure that pregnant people,

Looking ahead, Penta is expanding its research horizon by strengthening the integration between basic science, translational research and clinical trials. Over recent years, the Foundation has worked with partners to…

Neonatal sepsis remains a leading cause of newborn mortality across Africa, requiring not only effective antibiotic treatments but also research that is grounded in the needs and realities of families.

In 2025, Penta reached a key milestone by strengthening frontline capacity in paediatric HIV care through the THRIVE Advanced HIV Disease training in Mozambique. Delivered in Maputo in September,

This article was written by Michael Davis Tira, Computer Security Incident Response Team (CSIRT) Representative, Data & Infrastructure Team Manager, and Silvia Cavallo,

Historically, pregnant individuals and infants have been routinely excluded from clinical research under the guise of protection. The PIPELINE project serves as a critical response to this systemic gap, reframing…

In 2025, Penta concluded the VERDI project, a major European collaboration launched to understand the impact of SARS‑CoV‑2 variants and mpox on children and pregnant people. Beyond its scientific outputs,

In 2025, Penta reached a major milestone with the completion of the EPPICC paediatric study on dolutegravir (DTG), a key antiretroviral medicine used in the treatment of children and adolescents…