Publications

SARS-CoV-2 Infection and Hospitalization in Immunocompromised Children: A Population-Based Study

2024

Authors: Di Chiara C, Giugni A, Le Prevost M, Boracchini R, Barbieri E, Lupattelli A, Giaquinto C, Donà D, Cantarutti A.

Presented at: ICAR-CROI Awards for young Italian investigators, March 2024

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Pharmacokinetics of once-daily DTG/3TC FDC in children living with HIV: D3/PENTA21 sub-study

2024

Authors: Bevers HAL, Chan KM, Bbuye D, Kekitiinwa RA, Kityo C, Kaudha E, Ahimbisibwe MG, Arumugam T, Moloantoa T, Boles J, Deprez I, Giaquinto C, Turkova A, Colbers A for the D3/Penta21 trial team

Presented at: CROI 2024

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HIV-1 Reservoir Dynamics in Children With Early Treated, Perinatally-Acquired HIV: Does Sex Matter?

2024

Authors: Reddy K, Molechan C, Dominguez-Rodriguez S, Smith T, Spyer M, Lichterfeld M, Rojo P, Giaquinto C, Rossi P, Palma P, Isaacs M, Cardoso L, Liberty A, Estevao L, Tagarro A, Ndung’u T for EPIICAL

Presented at: CROI 2024

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SARS-CoV-2 Infection and Hospitalization in Immunocompromised Children: A Population-Based Study

2024

Authors: Di Chiara C, Giugni A, Le Prevost M, Boracchini R, Barbieri E, Lupattelli A, Giaquinto C, Donà D, Cantarutti A.

Presented at: CROI 2024

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Risk of SARS-CoV-2 Reinfection in Children Within the 12 Months Following Mild COVID-19: Insights From a Survey Study

2024

Authors: Di Chiara C, Boracchini R, Cantarutti A, Kakkar F, Oletto A, Padoan A, Donà D, Giaquinto C.

Published in: The Pediatric Infectious Disease Journal

Outcomes Following Prenatal Exposure to Raltegravir: A Multi-Cohort European Study

2024

Authors: Sconza R, Fernandes G, Aebi-Popp K, Ene L, Frick A, Gamell A, Ramos IM, Kahlert C, Peters H, Tato PML, Samarina A, Giaquinto C, Thorne C for the EPPICC Pregnancy Study Group

Presented at: CROI 2024

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ODYSSEY 192-week follow-up evidences superior efficacy of DTG for children on first/second-line ART

2024

Authors: Mujuru AH, White E, Kekitiinwa A, Lugemwa A, Kityo C, Musoke P, Cressey RT, Variava E, Violari A, Archery M, Cotton M, Puthanakit T, Rojo P, Turkova A

Presented at: CROI 2024

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Causes of death after early ART in infants living with HIV from 3 sub-Saharan African countries

2024

Authors: Tagarro A, Fernández-Luis S, Dominguez-Rodriguez S, Ballesteros A, Kuhn L, Cotton FM, Giaquinto C, Rossi P, Spyer M, Otwombe K, Behuhuma O, Vaz P, Foster C, Rojo P, for EPIICAL

Presented at: CROI 2024

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An efficient envelope genotypic assay to identify bNab susceptibility in infants with HIV

2024

Authors: Delaney EK, Kearney FM, Bester AP, Coetzee N, Engelbrecht S, Giaquinto C, Rossi P, Barnabas LS, Spyer JM, Litcherfeld M, Tagarro A, Lombard C, Cotton FM, Zyl vUG and EPIICAL Consortium

Presented at: CROI 2024

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1 in 5 sub-Saharan infants switches from undetectable to detectable HIV viral load during follow-up  

2024

Authors: Fernández-Luis S, Dominguez-Rodriguez S, Kuhn L, Cotton M, Giaquinto C, Rossi P, Rensburg JVA, Violari A, Lain GM, Lopez-Varela E, Sylla M, Amugue P, Rojo P, Tagarro A for EPIICAL Consortium

Presented at: CROI 2024

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Major revision version 12.0 of the European AIDS Clinical Society guidelines 2023

2024

Authors: Ambrosioni J, Levi L, Alagaratnam J, Van Bremen K, Mastrangelo A, Waalewijn H, Molina JM, Guaraldi G, Winston A, Boesecke C, Cinque P, Bamford A, Calmy A, Marzolini C, Martínez E, Oprea C, Welch S, Koval A, Mendao L, Rockstroh JK; EACS Governing Board.

Published in: HIV Medicine

Core Outcome Measurement Set for Research and Clinical Practice in Post COVID-19 Condition (Long COVID) in Children and Young People: An International Delphi Consensus Study “PC-COS Children”

2024

Authors: Seylanova N, Chernyavskaya A, Degtyareva N, Mursalova A, Ajam A, Xiao L, Aktulaeva K, Roshchin P, Bobkova P, Aiyegbusi OL, Anbu AT, Apfelbacher C, Asadi-Pooya AA, Ashkenazi-Hoffnung L, Brackel C, Buonsenso D, de Groote W, Diaz JV, Donà D, …, Thorne C, Vijverberg S, Warner JO, Were WM, Williamson PR, Munblit D.

Published in: European Respiratory Journal

Age-specific transmission dynamics of SARS-CoV-2 during the first two years of the pandemic

2024

Authors: Boldea O, Alipoor A, Pei S, Shaman J, Rozhnova G.

Published in: PNAS Nexus

How does post COVID differ from other post-viral conditions in childhood and adolescence (0–20 years old)? A systematic review

2024

Authors: Minotti C, McKenzie C, Dewandel I, Bekker C, Sturniolo G, Doni D, Giaquinto C, Van Der Zalm MM, Donà D.

Published in: eClinical Medicine

Epidemic graph diagrams as analytics for epidemic control in the data-rich era

2024

Authors: Valdano E, Colombi D, Poletto C, Colizza V.

Published in: Nature Communications

Clinical spectrum of disease and outcomes in children with Omicron SARS-COV-2 infection in Cape Town, South Africa

2024

Authors: Bekker C, Dewandel I, Redfern A, McKenzie C, Lishman J, Verhagen LM, Claassen M, Wilson S, Dunbar R, Bosch C, van Zyl G, Preiser W, Goussard P, Rabie H, van der Zalm MM.

Published in: IJTLD OPEN

Changing character and waning impact of COVID-19 at a tertiary centre in Cape Town, South Africa

2023

Authors: Hermans LE, Booysen P, Boloko L, Adriaanse M, de Wet TJ, Lifson AR, Wadee N, Papavarnavas N, Marais G, Hsiao NY, Rosslee MJ, Symons G, Calligaro GL, Iranzadeh A, Wilkinson RJ, Ntusi NAB, Williamson C, Davies MA, Meintjes G, Wasserman S.

Published in: Southern African journal of infectious diseases

Simultaneous pharmacokinetic modeling of unbound and total darunavir with ritonavir in adolescents: a substudy of the SMILE trial

2023

Authors: Abdalla S, Compagnucci A, Riault Y, Chan KM, Bamford A, Nolan A, Ramos TJ, Constant V, Nguyen T, Zheng Y, Tréluyer J, Froelicher-Bournaud L, Neveux N, Saidi Y, Cressey RT, Hirt D on behalf of the SMILE study group

Published in: Antimicrobial Agents and Chemotherapy

Stronger and durable SARS-CoV-2 immune response to mRNA vaccines in 5–11 years old children with prior COVID-19

2023

Authors: Di Chiara C, Cantarutti A, Petrara MR, Bonfante F, Benetti E, Boracchini R, Bosa L, Carmona F, Cosma C, Cotugno N, Le Prevost M, Martini G, Meneghel A, Pagliari M, Palma P, Ruffoni E, Zin A, De Rossi A, Giaquinto C, Donà D, Padoan A.

Published in: Vaccine

Longevity of mucosal and systemic SARS-CoV-2 antibodies in South African vs Dutch children with respiratory tract infections

2023

Authors: van Weelden G, Dewandel I, de Jonge MI, Redfern A, Bekker C, Lochan H, van der Gaast C, Van Niekerk M, Mentor M, Mfazwe A, Fröberg J, Diavatopoulos D, Donà D, Rabie H, van der Zalm M, Verhagen LM.

Presented at: International Congress of Immunology (IUIS)

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Navigating the COVID-19 Pandemic for Participant Recruitment and Follow-up: Experiences from the PediCAP Clinical Trial Consortium

2023

Authors: Kiggwe A, Nalwanga D, Tagoola A, Madhi S, Moore PD, Archary M, Mulenga V, Mujuru AH, Sacarlal J, Buck WC, Sidat M, Nguyen H, Haque F, Dennis E, Clements M, Murphy B, Spittle B, Viero F, Bielicki J, Musiime V,  Sharland M

Presented at: The EDCTP Forum 2023

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External factors affecting recruitment in a global paediatric pneumonia trial: lessons learned from PediCAP

2023

Authors: Pillay K, Archary M, Bielicki J, Buck WC, Clements M, Dennis E, Goelen J, Haque F, Kiggwe A, Madhi S, Moore PD, Mujuru AH, Mulenga V, Murphy B, Musiime V, Nalwanga D, Nguyen H, Sacarlal J, Sidat M, Spittle B, Tagoola A, Viero F, Sharland M

Presented at: The EDCTP Forum 2023

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Building a national network for inpatient pediatric clinical research in Mozambique 

2023

Authors: Sacarlal WJ, Buck C, Passanduca A, Macassa E, Saíde A, Chhaganlal K, Gafur M, Seni A, Machava S, Martins L, Issa F, Macanze E, Manjate N, Chaúque S, Langa S, Sidat M, Cassia U, Salimo A, Mavume C, Massitela C, Maieca A, Joaquim W, Martins S, Adriano Q, Zandamela M, Bramugy J, Bassat Q, Moraleda C, Tagarro A, Sharland M, Rojo P

Presented at: The EDCTP Forum 2023

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Receipt of intravenous co-amoxiclav challenged eligibility screening for the PediCAP Trial in Johannesburg, South Africa 

2023

Authors: Moore PD, Waggie Z, Nkosi S, Nkosi L, Kumalo N, Nkumana N, Zulu N, Dangor Z, Sharland M, Madhi S

Presented at: The EDCTP Forum 2023

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‘Nothing about us without us’: Multi-country adolescent patient-led recruitment information in the Long-Acting Treatment in Adolescents(LATA) trial – an animated video to compliment ‘traditional’ participant information  

2023

Authors: Conway M, Jafta L, Shibemba M, South A, Kityo Mutuluuza C, Bwakura-Dangarembizi M, Siika A, Archary M, Akabwai GP, Resty Babirye Okello, Mugerwa H, Nathoo K, Mujuru H, Chidziva E, Bhiri J, Nyandiko W, Kirui V, Kiilu C, Mosia R, Mngqbisa R, Ngwenya N, Seunanden T, Namukway S, Seeley J, Thomason M, Bush M, Dodds B, Ford D, Apoto N, Pett SL, Kekitiinwa-Rukyalekere A on behalf of the BREATHER Plus Consortium 

Presented at: The EDCTP Forum 2023

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Global adolescent HIV clinical trials: co-produced adolescent-friendly research information to support real informed assent/consent in the Long-acting treatment in Adolescents (LATA) trial 

2023

Authors: Conway M, Jafta L, Shibemba M, South A, Kityo Mutuluuza C, Bwakura-Dangarembizi M, Siika A, Archary M, Akabwai GP, Resty Babirye Okello, Mugerwa H, Nathoo K, Mujuru H, Chidziva E, Bhiri J, Nyandiko W, Kirui V, Kiilu C, Mosia R, Mngqbisa R, Ngwenya N, Seunanden T, Namukway S, Seeley J, Thomason M, Bush M, Dodds B, Ford D, Apoto N, Pett SL, Kekitiinwa-Rukyalekere A, on behalf of the BREATHER Plus Consortium 

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Findings from global consultations with adolescents living with HIV on the acceptability and accessibility of long-acting injectable ART

2023

Authors: Jafta L, Conway M, Davidson C, Ely A, Maciel Da Silva M, Peralta F, Saisaengjan C, Senyondo Nakawesi, J

Presented at:  International Workshop on HIV & Adolescence 2023

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Prediction of C-reactive protein dynamics during meropenem treatment in neonates and infants

2023

Authors: Soeorg H, Padari H, Ilmoja M-L, Herodes K, Kipper K, Lutsar I, Metsvaht T, NeoMero Consortium

Published in: British Journal of Clinical Pharmacology

Persistence of anti-SARS-CoV-2 antibodies in children and adults / Persistenza di anticorpi anti-SARS-CoV-2 in bambini e adulti

2023

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Exploring associations between Mpox-related health outcomes and HIV status

2023

Authors: Nicolò Girometti

Presented at: EACS 2023

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Pregnancy and neonatal outcomes following prenatal exposure to dolutegravir: the DOLOMITE EPPICC study

2023

Authors: Thorne C, Aebi-Popp K, Ene L, Floridia M, Gamell A, Illan M, Peters H, Samarina A, Fernandes G, Sconza R, Ragone L, Giaquinto C, Vannappagari V

Presented at: EACS 2023

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SARS-CoV-2 transmission patterns in educational settings during the Alpha wave in Reggio-Emilia, Italy

2023

Authors: Molina Grané C, Mancuso P, Vicentini M, Venturelli F, Djuric O, Manica M, Guzzetta G, Marziano V, Zardini A, d’Andrea V, Trentini F, Bisaccia E, Larosa E, Cilloni S, Cassinadri MT, Pezzotti P, Ajelli M, Rossi PG, Merler S, Poletti P.

Published in: Epidemics

Behavioral Changes Associated With COVID-19 Vaccination: Cross-National Online Survey

2023

Authors: De Gaetano A, Bajardi P, Gozzi N, Perra N, Perrotta D, Paolotti D.

Published in: Journal of Medical Internet Research

What explains the poor contraction of the viral load during paediatric HIV infection?

2023

Authors: Schröter J & De Boer R

Published in: Journal of Theoretical Biology 2023

Optimising kangaroo care to reduce neonatal severe infection/sepsis and resistant bacterial colonisation among high-risk infants in neonatal intensive care: a pragmatic, multicentre, parallel cluster randomised hybrid implementation–effectiveness trial (NeoDeco)

2023

Authors: Martin J, Cook A, Bielicki J, and the NeoIPC Consortium

Presented at: jENS Congress

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Effect of dolutegravir on folate, vitamin B12 and mean corpuscular volume levels among children and adolescents with HIV: a sub-study of the ODYSSEY randomized controlled trial 

2023

Authors: Barlow-Mosha L.N., Ahimbisibwe G.M., Chappell E., Amuge P.M., Nanduudu A., Kaudha E., Amukele T., Balamusani D., Kafufu B., Nimwesiga A., Kataike H., Namwanje R., Kasangaki G., Mulindwa A., Muzorah, G.A., Bbuye D., Musiime V., Mujyambere E., Ssenyonga M., Mulima D., Kyambadde R.C., Namusanje J., Isabirye R., Nabalamba M., Nakirya B.M., Kityo C., Kekitiinwa A.R., Giaquinto, C., Copp A., Gibb, D.M., Ford, D., Musoke P., Turkova A

Published in: Journal of the International AIDS Society

Relative bioavailability of dolutegravir (DTG) and emtricitabine/tenofovir alafenamide fumarate (F/TAF) administered as paediatric tablet formulations in healthy volunteers 

2023

Authors: Bevers LAH., Kamphuis AEM., van der Wekken-Pas LC, Leisegang R, Lewis L, Burger DM, Colbers A

Presented at: International Workshop on Clinical Pharmacology of HIV, Hepatitis, and Other Antiviral Drugs 2023

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Comparative study showed that children faced a 78% higher risk of new-onset conditions after they had COVID-19

2023

Authors: Di Chiara C, Barbieri E, Chen YX, Visonà E, Cavagnis S, Sturniolo G, Parca A, Liberati C, Cantarutti L, Lupattelli A, Le Prevost M, Corrao G, Giaquinto C, Donà D, Cantarutti A.

Published in: Acta Paediatrica

COVID-19 and MIS-C treatment in children—results from an international survey

2023

Authors: Donà D, Minotti C, Masini T, Penazzato M, Van Der Zalm MM, Judd A, Giaquinto C, Lallemant M & Survey Respondents Consortium.

Published in: European Journal of Pediatrics

Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV

2023

Authors: Ruel T, Penazzato M, Zech JM, Archary M, Cressey TR, Goga A, Harwell J, Landovitz RJ, Lain MG, Lallemant M, Namusoke-Magongo E, Mukui I, Permar SR, Prendergast AJ, Shapiro R, Abrams EJ.

Published in: Global Health: Science & Practice

The Smooth Away From Expected (SAFE) non-inferiority frontier: theory and implementation with an application to the D3 trial

2023

Authors: Quartagno, M, Chan, M, Turkova, A et al.

Published in: Trials

Sensitive HIV-1 DNA Pol Next-Generation Sequencing for the Characterisation of Archived Antiretroviral Drug Resistance

2023

Authors: Botha JC, Byott M, Spyer MJ, Grant PR, Gärtner K, Chen WX, Burton J, Bamford A, Waters LJ, Giaquinto C, et al.

Published in: Viruses

Minimising school disruption under high incidence conditions due to the Omicron variant in France, Switzerland, Italy, in January 2022

2023

Authors: Colosi E, Bassignana G, Barrat A, Lina B, Vanhems P, Bielicki J, Colizza V.

Published in: MedRxiv (preprint) and Eurosurveillance

Reconstruction of SARS-CoV-2 outbreaks in a primary school using epidemiological and genomic data

2023

Authors: Kremer C, Torneri A, Libin PJK, Meex C, Hayette MP, Bontems S, Durkin K, Artesi M, Bours V, Lemey P, Darcis G, Hens N, Meuris C.

Published in: Epidemics

Clinical features of COVID-19 in Italian outpatient children and adolescents during Parental, Delta, and Omicron waves: a prospective, observational, cohort study

2023

Authors: Di Chiara C, Boracchini R, Sturniolo G, Barbieri A, Costenaro P, Cozzani S, De Pieri M, Liberati C, Zin A, Padoan A, Bonfante F, Kakkar F, Cantarutti A, Donà D, Giaquinto C.

Published in: Frontiers in Pediatrics

Virological suppression and weight gain in children in Europe on dolutegravir compared to protease inhibitors: a propensity score analysis 

2023

Presented by: Siobhan Crichton 

Presented at: International Workshop on HIV and Pediatrics

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Uptake of integrase inhibitors and virological response in children living with HIV in Europe & Thailand from 2010 to 2020  

2023

Presented by: Jeannie Collins

Presented at: IAS and International Workshop on HIV and Pediatrics

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Uptake and outcomes of tenofovir alafenamide fumarate (TAF) –based therapy in children and young people living with HIV (CLWHIV) in the European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC)

2023

Presented by: Siobhan Crichton

Presented at: IAS and International Workshop on HIV and Pediatrics

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Impact of COVID-19 pandemic on HIV viral load testing in paediatric HIV clinics in the European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC)  

2023

Presented by: Siobhan Crichton

Presented at: IAS and International Workshop on HIV and Pediatrics

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Incidence and severity of SARS-CoV-2 infection in children and young people with HIV in Europe

2023

Authors: Chappell E, Bamford A, Sanchez AB, Goetghebuer T, Marques L, Navér L, Noguera-Julian A, Talarek E, Plotnikova Y, Samarina A, Ene L, Spoulou V, Collins IJ, Navarro ML, Plynsky AA, Chapygina Y, Fertikh E, Soeria-Atmadja S, Doerholt K, Welch S, Crichton S, Jackson C, Judd A, Scott K

Published in: AIDS

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