Sharing our understanding of the immune response of children living with HIV

12 Mar, 2021

EPIICAL is proud to have presented four abstracts at the CROI conference this year, sharing updated information on viral decay and the immune response of children living with HIV who begin treatment early in life.


  • EFFECT OF HIV ON IMMUNE ACTIVATION AND EXHAUSTION IN CD4 AND CD8 T CELLS IN INFANTS Stefano Rinaldi, Vinh B. Dinh, Suresh Pallikkuth, Lesley D. Armas, Nadia Sitoe, Rajendra Pahwa, Nicola Cotugno, Paula Vaz, Paolo Palma, MariaGrazia Lain, Savita G. Pahwa
  • DYNAMICS OF INTACT PROVIRAL SEQUENCES IN EARLY TREATED HIV-1 CLADE C–INFECTED INFANTS Catherine K. Koofhethile, Stefano Rinaldi, Yelizaveta Rassadkina, Vinh B. Dinh, Ce Gao, Suresh Pallikkuth, Pilar Garcia-Broncano, Lesley D. Armas, Rajendra Pahwa, Nicola Cotugno, Maria Grazia Lain, Paolo Palma, Roger Shapiro, Savita G. Pahwa, Mathias Lichterfeld
  • VIRAL-RESERVOIR LANDSCAPE IN EARLY-TREATED VERTICALLY HIVINFECTED ADOLESCENTS Libera Sessa, Xiaodong Lian, Ce Gao, Nicola Cotugno, Alessandra Ruggiero, Xu G. Yu, Paolo Palma, Mathias Lichterfeld
  • FASTER INITIAL VIRAL DECAY IN FEMALE CHILDREN LIVING WITH HIV Sara Dominguez-Rodr.guez, Miquel Serna-Pascual, Caroline Foster, Paolo Palma, Eleni Nastouli, Anita De Rossi, Javier Seoane, Paolo Rossi, Carlo Giaquinto, Alfredo Tagarro, Pablo Rojo, for the EPIICAL Consortium

Follow this link to view the Abstract booklet


The CROI conference, which was held virtually from March 6-10, provided delegates with the opportunity to present new data on their HIV research and development studies. CROI is a long-standing conference that has provided a forum for scientists and investigators to present, discuss and critique research into human retroviruses and associated diseases. Over the years, the congress has facilitated the presentation of important discoveries and contributed to the acceleration in the understanding and progress in HIV/AIDS research.

The EPIICAL Consortium has successfully conducted studies on children living with HIV by setting up different well-characterized cohorts in Europe and Africa. The presented abstracts explored the factors that affect the immune response and the viral dynamics in children with a special focus on the early antiretroviral treatment. All these data are really informative and represent the basis to tailor immune therapeutic strategies in HIV infected children.

Thank you to all the authors for your invaluable contribution towards improving the understanding of HIV infection in children.

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