The ORCHESTRA project, launched in Dec 2020, has a vision to efficiently generate rigorous evidence to improve the prevention and treatment of COVID-19 and to rapidly provide a structured platform to test vaccines as soon as they are available. Visit the ORCHESTRA website. View ORCHESTRA publications.


Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic

ORCHESTRA is a three-year international research project aimed at tackling the coronavirus pandemic by establishing an international large-scale cohort for the conduction of retrospective and prospective studies to generate evidence to improve the prevention and treatment of COVID-19 and to be better prepared for future pandemics. As a beneficiary of the project, Penta will grant its scientific contribution in elaborating and analysing data of the paediatric cohorts included in the project. Additionally, it will contribute to the ORCHESTRA fragile population cohorts with pregnancy and paediatric cohorts across its network.

Why is ORCHESTRA needed?

ORCHESTRA project provides an innovative approach to learn from the SARS-CoV-2 health crisis and derive recommendations for increasing preparedness for future outbreaks. The ORCHESTRA cohort will include SARS-CoV-2 infected and non-infected individuals of all ages and conditions. This will enable a retrospective evaluation of risk factors for the disease acquisition and progression, with a prospective follow-up aimed at exploring long term consequences and analysis of vaccination response.

What is ORCHESTRA’s goal?

The main outcome of the project is the creation of a new pan-European cohort, that will consist of both existing and new large-scale population cohorts from European and non-European countries. ORCHESTRA will develop evidence-based recommendations for effective prevention, protection and optimized treatment of COVID-19 patients (including long-term consequences) with a special focus on ‘at risk’ populations, including healthcare workers and fragile individuals.

ORCHESTRA has received funding from the European Union’s Horizon 2020 
research and innovation programme under grant agreement No 101016167.