Treatment Guidelines

Treatment Guidelines

The 2019 Penta guidelines for first and second line antiretroviral treatment are now available. The aim of these guidelines is to provide a concise reference document to guide antiretroviral choices for children and adolescents with perinatally acquired HIV in the European region. This document will be updated at regular intervals by the guidelines writing group or as significant new data or evidence becomes available.

These guidelines supersede the first and second line recommendations published in the 2015 Treatment Guidelines with associated 2016 update.

A document summarising responses to the public consultation and writing group conflict of interest statements are available on request from


17th September, 2019


We would like to update you on our recent activities