2017
Authors: Sáfadi MA, Nascimento-Carvalho CM
Published in: Pediatr Infect Dis J.2017;36(3):333-336
Abstract After remaining related to few sporadic cases in limited regions for more than half century since its discovery, Zika virus (ZIKV) was recently introduced into the Western Hemisphere, first in Brazil and then spreading very rapidly in the Americas. Unexpectedly, an increased incidence of microcephaly and other neurologic malformations in fetuses born to mothers infected with ZIKV during pregnancy was reported in Brazil,
2017
Authors: Garcez PP, Nascimento JM, de Vasconcelos JM, et al.
Published in: Sci Rep. 2017 Jan 23;7:40780
Abstract Zika virus (ZIKV) has been associated with microcephaly and other brain abnormalities; however, the molecular consequences of ZIKV to human brain development are still not fully understood. Here we describe alterations in human neurospheres derived from induced pluripotent stem (iPS) cells infected with the strain of Zika virus that is circulating in Brazil.
2017
Authors: Sacramento CQ, de Melo GR, de Freitas CS, et al.
Published in: Sci Rep.2017 Jan 18;7: 40920
Abstract Zika virus (ZIKV) is a member of the Flaviviridae family, along with other agents of clinical significance such as dengue (DENV) and hepatitis C (HCV) viruses. Since ZIKV causes neurological disorders during fetal development and in adulthood,
2017
Authors: Gaskell KM, Houlihan C, Nastouli E, Checkly AM
Published in: Emerg Infect Dis.2017;23(1):137-139
Abstract Zika virus is normally transmitted by mosquitos, but cases of sexual transmission have been reported. We describe a patient with symptomatic Zika virus infection in whom the virus was detected in semen for 92 days. Our findings support recommendations for 6 months of barrier contraceptive use after symptomatic Zika virus infection.
2017
Authors: Melbourne-Chambers R., Christie CD, Greenaway E., Bullock R
Published in: West Indian Med J.2016;65(3):425-430
Abstract Dengue, Chikungunya Fever (CHIKV) and Zika virus (ZIKV) are all transmitted by the Aedes aegypti mosquito and are currently circulating in Jamaica. Jamaica has been experiencing a ZIKV epidemic since February 2016. At the University Hospital of the West Indies (UHWI),
2017
Authors: Iovine NM, Lednicky J, Cherabuddi K, et al.
Published in: Clin Infect Dis. 2017;64(1): 72–75.
Abstract Zika virus and dengue virus serotype 2 were isolated from a patient with travel to Haiti who developed fever, rash, arthralgias, and conjunctivitis. The infecting Zika virus was related to Venezuelan and Brazilian strains but evolved along a lineage originating from strains isolated in 2014 in the same region of Haiti.
2017
Authors: Fuller TL, Calvet G, Genaro Estevam C, et al.
Published in: PLoS One. 2017;12(11):e0188002
Abstract: The burden of arboviruses in the Americas is high and may result in long-term sequelae with infants disabled by Zika virus infection (ZIKV) and arthritis caused by infection with Chikungunya virus (CHIKV).
2017
Authors: Nelson B, Melbourne-Chambers R, Christie CDC
Published in: West Indian Med J. Published Online: December 20, 2017
Abstract Zika Virus is neurotropic. We report two children from the Caribbean island of Grenada, a three-year-old with acute neuro-inflammation who had intractable seizures, meningo-encephalitis, CSF pleocytosis and Zika IgM positive acute serology and a four-year-old with acute demyelinating encephalomyelitis manifesting as generalized seizures,
2017
Authors: Schwarz ER
Published in: Curr Opin Virol. 2017;27:71-77
Abstract Measles, mumps, and rubella have recently taken the stage as re-emerging diseases of public health importance-particularly in regards to the consequences seen with perinatal infections. Effective vaccination strategies have successfully reduced the spread of measles, mumps, and rubella in the United States, but a current trend of increased vaccination hesitancy,
2017
Authors: da Silva IRF, Frontera JA, Bispo de Filippis AM, Nascimento OJMD
Published in: JAMA Neurol.2017;74(10):1190-1198
Importance There are no prospective cohort studies assessing the incidence and spectrum of neurologic manifestations secondary to Zika virus (ZIKV) infection in adults.
Objective To evaluate the rates of acute ZIKV infection among patients hospitalized with Guillain-Barré syndrome (GBS),
2017
Authors: Bosch I, de Puig H, Hiley M, et al.
Published in: Sci Transl Med. 2017 Sep 27;9(409)
Abstract The recent Zika virus (ZIKV) outbreak demonstrates that cost-effective clinical diagnostics are urgently needed to detect and distinguish viral infections to improve patient care. Unlike dengue virus (DENV), ZIKV infections during pregnancy correlate with severe birth defects,
2017
Authors: Barreto-Vieira DF, Jacome FC, da Silva MAN, et al.
Published in: PLoS One. 2017;12(9):e0184397
Abstract Zika virus (ZIKV) is a member of the flavivirus genus, and its genome is approximately 10.8 kilobases of positive-strand RNA enclosed in a capsid and surrounded by a membrane. Studies on the replication dynamics of ZIKV are scarce,
2017
Authors: Balmaseda A, Stettler K, Medialdea-Carrera R, et al.
Published in: Proc Natl Acad Sci U S A. 2017;114(31):8384-8389
Abstract Zika virus (ZIKV) is a mosquito-borne flavivirus that emerged recently as a global health threat, causing a pandemic in the Americas. ZIKV infection mostly causes mild disease, but is linked to devastating congenital birth defects and Guillain-Barré syndrome in adults.
2017
Authors: Braga JU, Bressan C, Dalvi APR, et al.
Published in: PLoS One.2017;12(6):e0179725.
Background Zika is a new disease in the American continent and its surveillance is of utmost importance, especially because of its ability to cause neurological manifestations as Guillain-Barrésyndrome and serious congenital malformations through vertical transmission. The detection of suspected cases by the surveillance system depends on the case definition adopted.
2017
Authors: Nascimento OJM, Frontera JA, Amitrano DA, Bispo de Filippis AM, Da Silva IRF; RIO-GBS-ZIKV Research Group
Published in: Neurology 2017;88(24):2330-2332
2016
Authors: Safadi MA
Published in: Amer J Perinatol.2016; 33(11): 1029-1031
Abstract Zika virus (ZIKV) is an emerging arthropod-borne, enveloped RNA virus of the Flaviviridae family, which belongs to the genus Flavivirus, related to dengue, yellow fever, Japanese encephalitis, and West Nile viruses. Two major lineages, African and Asian, have been identified through phylogenetic analyses.
2016
Authors: Davidson T., Vickers I., Christie CD
Published in: West Indian Med J 2016;65(3);442-449
Background Dengue fever is hyper-endemic in Jamaica with exponential rates of infection in successive outbreaks. The absence of local data and the potential for massive outbreaks in a country where a third of the population are children formed the basis for this study.
2016
Authors: Christie CD, Melbourne-Chambers R, Ennevor J, et al.
Published in: West Indian Med J 2016;65(3);431-437
Background Chikungunya virus entered the Caribbean for the first time in 2013 and Jamaica experienced its maiden epidemic with Chikungunya Fever in 2014. We aimed to describe the public health effects and describe the clinical features in children and adolescents in Jamaica.
2016
Authors: Webster-Kerr K, Christie CDC, Grant A, et al.
Published in: West Indian Med J. 2016;65(1):243-249
Background Jamaica, along with the Americas, experienced major epidemics of arboviral diseases transmitted by the Aedes aegypti mosquito in recent years. These include dengue fever in 2012, chikungunya fever in 2014 and Zika virus infection (ZIKV) in 2016. We present the emergence of the ZIKV epidemic in Jamaica and outline the national response.
2016
Authors: Oliveira DB, Almeida FJ, Durigon EL, et al.
Published in: N Engl J Med. 2016. 22;375(12):1202-4
The presence of Zika virus (ZIKV) infection has been associated with microcephaly in multiple studies, although little is known about ZIKV shedding in congenitally infected infants. We report a case of a newborn who had continued viremia with ZIKV for at least 67 days after birth.
2016
Authors: Christie CD, Giaquinto C
Published in: West Indian Med J.2016;65(1):239-242
Abstract Zika virus epidemic now involves 72 countries, worldwide. Transmission is multimodal through mosquito bites and blood and body fluids. Zika virus causes Guillain Barre Syndrome syndrome and pregnancy complications including perinatal microcephaly. Diagnosis is complicated by subclinical infection in 80%,
2016
Authors: Bocanegra C, Sulleiro E, Soriano-Arandes A, et al.
Published in: Clin Microbiol Infect. 2016;22(7):648-50
This case series of two pregnant women infected with the Zika virus in Barcelona, Spain and provides an algorithm for diagnosing pregnant women with suspected ZIKV infection in non-endemic areas.
2016
Authors: Capua I
Published in: Nature. 2016;16;534(7607):326
This correspondence urges Brazil to speed up reforms to current biosecurity legislation, enabling sharing of vital Zika virus samples and information.
2016
Authors: Kednicky J, Beau De Rochars VM, El Badry M, et al.
Published in: PLoS Negl Trop Dis. 2016;10(4):e0004687
Background Zika virus (ZIKV), first isolated in Uganda in 1947, is currently spreading rapidly through South America and the Caribbean. In Brazil, infection has been linked with microcephaly and other serious complications,
2016
Authors: Solomon T, Baylis M, Brown D.
Published in: Lancet Infect Dis. 2016;16(4):402-404
This article comments on the origins and consequences of recent Zika virus outbreaks, highlighting the urgent need to address several key gaps in knowledge regarding this virus.
2016
Author: Bispo A
Published in: Bull World Health Organ. 2016;94:165–166
In this interview, Anna Bispo describes the history of Zika virus in Brazil, including its potential links to an increase in microcephaly cases, and describes groundbreaking work in Zika virus diagnostics and virology at the Oswaldo Cruz Foundation in Rio de Janeiro, Brazil.
2016