The REALITY (Reduction of EArly mortality in HIV-infected adults and children starting antiretroviral therapy) study is a randomized controlled trial run by the Medical Research Council Clinical Trials Unit in several sub-Saharan African countries.

The study investigates the effectiveness of 1) increasing potency of antiviral therapy, 2) augmented prophylaxis against opportunistic infections and 3) macronutrient intervention for reducing early mortality among children, adolescents and adults over a 12 week period.

This study is funded by Penta.


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