Study update


Apr, 2019

SMILE Clinical Trial: 100th Patient Enrolled

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The Penta-sponsored clinical trial SMILE has achieved a significant milestone by recruiting its 100th patient yesterday. The patient was enrolled at the Perinatal HIV Research Unit (PHRU) in Soweto, South Africa.  This is a wonderful result achieved through hard work and cooperation among the sites, the CTUs and the sponsor.



Oct, 2018

EPIICAL: enrollment has completed in the CARMA study!


September saw the CARMA study complete its enrollment target of 40 patients. Reservoir size assays have been performed, and primary statistical analyses are ongoing. Over the coming weeks, some results relating immunological and virological assays will be released and discussed internally within the EPIICAL Consortium at General Assembly meeting in November.



May, 2018

EARTH: first patient has been recruited!

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It is with great pleasure that we announce that the first patient in the EARTH study has been recruited. This encouraging news comes to us from the PHRU site in Soweto, South Africa. Now that all sites are open for recruitment, with some patients having already been screened, we are confident we will see more participants in the near future. This is the first of 150 children to be enrolled from one of 5 sites situated in South Africa and Mozambique. The EARTH project, nested within the EPIICAL platform, is a prospective multicentre, low-interventional study of HIV+ perinatally […]



Nov, 2016

The ZIKAction Kick-Off Meeting was a success!


The ZIKAction Kick-Off Meeting was held in Kingston, Jamaica at the University of West Indies from October 30th to November 1st. Thank you all for coming!! This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 734857.