c4c General Assembly
30 Jun, 2022
Between 13th-15th June 2022, around 140 beneficiaries of the c4c consortium met in Ghent Belgium for the c4c General Assembly. This was the first time since 2019 that the consortium…
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The D3 trial is open and recruiting fast!
30 Jun, 2022
A new trial opened in May, aiming to find out if children and young people living with HIV can take two anti-HIV medicines instead of three. The trial has already…
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SHIELD trial screens first two patients
28 Jun, 2022
The first two participants of the SHIELD trial (PENTA-22) were screened by Dr. Renate Strehlau and her team at Rahima Moosa Mother and Child Hospital, Johannesburg, South Africa in June 2022. SHIELD…
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EMA updates guideline on the treatment of bacterial infections
27 Jun, 2022
The European Medicines Agency (EMA) has published the final revised guideline on the evaluation of human medicines for the treatment of bacterial infections. The revised guideline reflects the outcome of recent discussions…
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The Penta Early Career Researchers (ECRs) have held the first Penta Cafè!
07 Jun, 2022
The first Penta Café, held on 19 May, was attended by ECRs from Europe and Africa who discussed ideas on the best way to get papers published, tips and learning…
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PediCAP surpasses 25% patient recruitment milestone
31 May, 2022
We are pleased to announce that the PediCAP trial have successfully passed its 25% recruitment milestone with more than 400 patients successfully randomised into their arms. PediCAP will determine whether…
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Penta ID Network Meeting (PIM) 2022
25 May, 2022
The Penta ID Network Meeting 2022 (PIM, 28-30 April 2022) gave our members – the Penta family – a great opportunity to meet face-to-face, after more than two years of distance due…
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Youth engagement and participation in clinical trials
20 May, 2022
Involving patients in our clinical trials is of utmost importance to us. Penta is dedicated to ensuring that the young people in our trials are included at various stages of…
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Penta at the Global Child Health Mini-Symposium in Oxford April 7th 2022
19 May, 2022
Penta was highly represented at the Mini-Symposium hosted by Green Templeton College – University of Oxford on the 7th of April 2022 entitled “Serving the children of the world: examining…
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Penta investigates cases of acute hepatitis of unknown origin in children
18 May, 2022
On 12 May, a Rapid Communication on the reported increase of acute hepatitis of unknown origin in children was published in Eurosurveillance. The paper outlines the extent and geographical distribution…
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RBDCOV initiates the first Phase III clinical trial of HIPRA’s Covid-19 vaccine in immunocompromised people
18 May, 2022
One of the objective of RBDCOV is to test whether the vaccine can reactivate or re-generate a protective immune response against the virus The RBDCOV project, in which Penta is…
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Capacitating the future of research in paediatric HIV
16 May, 2022
[vc_row][vc_column][vc_column_text]By design, capacity building is a fundamental part of the UNIVERSAL project. The aim of the project’s capacity building activities are to improve the ability of African and European young…
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The EPIICAL story
11 May, 2022
In 2016 the Early-treated Perinatally HIV-infected individuals: Improving Children’s Actual Life (EPIICAL) consortium began gathering scientists and clinicians specialising in paediatric HIV to work towards establishing new, scientific efforts on…
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PentaTr@ining 2022: online course kicks off!
25 Apr, 2022
Our interactive course PentaTr@ining 2022: ‘HIV & other Congenital Infections’ kicks off today! The innovative online programme comprises 6 interactive and in-depth training modules, a wide variety of real-life clinical cases for…
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Borrowing information across patient subgroups in clinical trials
23 Mar, 2022
An article by investigators within the ODYSSEY trial has been published as Open Access into BMC Medical Research Methodology. The investigators aimed to evaluate a treatment effect in a pre-defined subgroup…
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Dolutegravir dosing for children with HIV weighing less than 20 kg
23 Mar, 2022
The results of an ODYSSEY pharmacokinetic sub-study investigating dolutegravir (DTG) based antiretroviral (ARV) treatments for children weighing 3 to less than 20kg have recently been published in The Lancet HIV as an…
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What is PentaTr@ining
15 Mar, 2022
PentaTr@ining (formerly ‘Tr@inforPedHIV’) is a groundbreaking training platform for healthcare professionals caring for children, adolescents and pregnant women living with infectious diseases – with a particular focus on HIV and…
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WHO Paediatric ARV dosing dashboard
14 Mar, 2022
The WHO have developed a Paediatric ARV dosing dashboard which aims to support health care workers, researchers and policy makers in decisions around ARV dosing for children. It includes a…
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