ODYSSEY

Dolutegravir-based HIV treatment is better for babies and young children

2022

Babies and young children treated with the anti-HIV drug dolutegravir, in combination with other anti-HIV drugs, are more likely to keep the virus under control, compared to those treated with standard anti-HIV treatment combinations.

Read More

Double dose of dolutegravir to treat HIV in children also being treated for tuberculosis

2022

Results from a substudy of the ODYSSEY trial show that children being treated for tuberculosis (TB) and HIV at the same time can safely have the anti-HIV medicine dolutegravir twice a day.

Read More

Borrowing information across patient subgroups in clinical trials

2022

An article by investigators within the ODYSSEY trial has been published as Open Access into BMC Medical Research Methodology. The investigators aimed to evaluate a treatment effect in a pre-defined subgroup of interest while borrowing information from a separate patient subgroup,

Read More

Dolutegravir dosing for children with HIV weighing less than 20 kg

2022

The results of an ODYSSEY pharmacokinetic sub-study investigating dolutegravir (DTG) based antiretroviral (ARV) treatments for children weighing 3 to less than 20kg have recently been published in The Lancet HIV as an Open Access article.

Read More

Once-daily DTG more effective in treating HIV in children

2021

The ODYSSEY trial’s final paper Dolutegravir as First- or Second-Line Treatment for HIV-1 Infection in Children has been published in the New England Journal of Medicine.

Read More

ODYSSEY trial wins 2021 Hector Award

2021

It was announced at the 8th European AIDS Conference that Angela Colbers and David Burger received the Hector Research Award in HIV 2021 in clinical and/or epidemiological science on behalf of the ODYSSEY trial team!

Read More

New findings from the ODYSSEY trial confirm superiority of dolutegravir-based ART in younger children – A story by WHO

2021

WHO welcomes new findings presented today at International Pediatric HIV Workshop on the superiority of dolutegravir (DTG)-based regimens in young children.

Children living with HIV continue to be left behind by the global AIDS response.

Read More

ODYSSEY team at Radboud receives the RIHS Societal Award 2020

2021

As the world continues to raise its voice towards improving HIV treatment for children, the contributions made by the ODYSSEY trial have not gone unnoticed and as a result, has earned researchers the Radboud Institute for Health Sciences Societal Impact Award.

Read More

ODYSSEY trial finds new drug is better for treating children living with HIV

2021

The anti-HIV drug Dolutegravir improves outcomes for children with HIV infection when given in a 3-drug combination. These results come from the ODYSSEY trial which was presented yesterday at the Conference on Retroviruses and Opportunistic Infections.

Read More

EU grants Marketing Authorisation to first-ever dispersible-tablet dolutegravir

2021

On 12 January 2021, the European Medicine Agency approved the use of dolutegravir 5mg dispersible tablets for treating HIV in young children living in Europe. This decision was based, in part,

Read More

Cheaper HIV treatment for children: a report in The Lancet

2020

With the world engulfed by the COVID-19 pandemic, you may not have heard about some of the breakthroughs that the scientific community has made in the treatment of paediatric HIV. 

Read More

European Medicines Agency approves use of Dolutegravir 5 mg dispersible tablet for younger children living with HIV

2020

On November 12th, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) issued a positive opinion recommending marketing authorisation for dolutegravir 5mg dispersible tablets for young children living with HIV.

Read More

ODYSSEY: New website is online!

2019

We are pleased to announce the launch of the brand new ODYSSEY website!

Included among the various features on the site are a background of the study,

Read More