Publications

Trial design and enrolment characteristics of LATA (long-acting treatment in adolescents): A randomised, open-label, non-inferiority, 96-week trial evaluating the virological efficacy, safety, acceptability and quality-of-life of the dual long-acting injectable regimen cabotegravir/ rilpivirine compared to daily oral therapy in virologically suppressed adolescents with HIV-1 infection, aged 12 to <20 years, in Sub-Saharan Africa

2026

Authors: Anena D, Chappell E, Nazzinda R, Kiilu C, Chitsamatanga M, Arumugam T, Green A, Mutuluuza CK, Bwakura-Dangarembizi M, Siika A, Archary M, Jafta L, Namukwaya S, Seeley J, Akabwai G, Mugerwa H, Bevers L, Burger D, Walker S, Bamford A, South A, Apoto N, Bush M, Thomason MJ, Spittle B, Ford D, Kekitiinwa AR, Pett SL; LATA Trial Team.

Published in: Contemporary Clinical Trials

Household SARS-CoV-2 transmission during Omicron wave in Chiang Mai, Thailand: a prospective observational study

2026

Authors: Khamduang W, Suebtam P, Collins IJ, Sripan P, Chalom K, Hongjaisee S, Kham-Kjing N, Wangsaeng N, Inmonthian P, Pinasu A, Kohklang N, Arnal M, Spyer M, Steffens-Westerhof I, Aramrattana A, Lallemant M, Angkurawaranon C, Bruijning-Verhagen P, Ngo-Giang-Huong N; Thailand VERDI-RECOVER Study Team.

Published in: The Lancet Regional Health – Southeast Asia

Associations between virus single or coinfections and respiratory symptoms in young children; a community-based cohort study

2025

Authors: Hauser-van Westrhenen E, Junquera Guinovart L, Schuurman R, van Boven M, Bonten M, Bruijning-Verhagen P.

Published in: International Journal of Infectious Diseases

Late diagnosis of paediatric HIV infection in high-income countries: Lessons from the HIV Perinatal Virtual Clinic

2025

Authors: Curto C, Tritzali M, Bamford A, Bailey AC, Lyall EGH, Mackie NE, Tickner N, Foster C; on behalf of the PVC.

Published in: HIV Medicine

Epidemiological characteristics of Monkeypox Virus Clade Ib in the Democratic Republic of Congo: the impact of transmission mode

2025

Authors: Kremer C, Nundu SS, Vakaniaki EH, Brosius I, Mukari G, Munganga P, Bangwen E, Mujula Y, De Vos E, Van Dijck C, Houben S, Gressani O, Kacita C, Mukadi-Bamuleka D, Muyembe-Tamfum JJ, Mbala-Kingebeni P, Liesenborghs L, Hens N, Torneri A.

Published in: Nature Communications

Short- and Long-term Humoral Response of Immunosuppressed Children to SARS-CoV-2 BNT162b2 Vaccine

2025

Authors: Tagarro A, Gastesi I, Hotterbeekx A, Aguilera-Alonso D, Konnova A, Gupta A, Salso S, Berkell M, Plata MdC, Domínguez-Rodríguez S, Ballesteros Á, Manzanares Á, Oltra M, Villanueva S, Pinto C, Guillén R, Giaquinto C, Moraleda C, Kumar-Singh S.

Published in: Pediatric Infectious Disease Journal

A rapid time-resolved host gene expression signature predicts responses to antibiotic treatment in neonatal bacterial sepsis

2025

Authors: Parkinson EC, Watkins WJ, Edkins S, McLaren JE, Clements MN, Andrews R, Liberatore F, Lutsar I, Turner MA, Roilides E, Heath PT, Sharland M, Hill LF, Ghazal P; on behalf of the NeoVanc Consortium.

Published in: Science Translational Medicine

BNT162b2 mRNA COVID-19 vaccine effectiveness in pregnancy: Emulating trial NCT04754594 using observational data from Norwegian health registries

2025

Authors: Zidan M, Trinh N, Desalegn A, Smith LH, van Gelder M, Nordeng H, Lupattelli A.

Published in: Vaccine

Risk factors for antibiotic resistant bacterial colonisation in European Neonatal Units – results of the NeoIPC feasibility study

2025

Authors: Minotti C, Cook A, Berkell M, Bielicki J, on behalf of the NeoIPC Consortium.

Presented at: jENS Congress 2025

Major revision version 13.0 of the European AIDS Clinical Society guidelines 2025

2025

Authors: Ambrosioni J, Levi LI, Alagaratnam J, Sempere A, Mastrangelo A, Paioni P, Mussini C, Marzolini C, Nielsen SD, Béguelin C, Welch S, Koval A, Mendao L, Bamford A, Calmy A, Guaraldi G, Oprea C, Martínez E, Rockstroh JK, The EACS Governing Board.

Published in: HIV Medicine

Transição precoce para Amoxicilina oral: seguro e eficaz em crianças hospitalizadas com Pneumonia Grave

2025

Presented by: Sidat M. M

Presented at: Jornadas Nacionais de Saude

Impacto da passagem oral à Amoxicilina ou Co-amoxiclav e da duração da terapêutica antibiótica na eficácia, segurança e selecção da resistência antibiótica na Pneumonia severa infantil adquirida na comunidade (PAC) – ensaio clínico PediCAP

2025

Presented by: Sidat M. M, em nome da equipe do ensaio PediCAP

Presented at: Simpósio Pré-Evento, XIII Conferência Científica da UEM

Pediatric stewardship in Italy: a necessity, not an option – a National Multi-Society Expert Consensus on Antimicrobial and Diagnostic Stewardship (SIP, SITIP, SIMRI, SIAIP, SIMEUP, SIPPS, SICUPP, SIMIT, SIMPE, SIPINF, SIT, SIAATIP, SARNEPI, AIEOP, SIM, SITI, SIF, SIFACT, SITA, SIN)

2025

Authors: Donà D, Barbieri E, Brigadoi G, Barchitta M, Berardi A, Bosis S, Buchini S, Buonsenso D, Cagliero A, Campana BR, Capello F, Carrozzo R, Castagnola E, Cazzato S, Cesaro S, Chiappini E, Colomba C, Comar M, De Alessandri A, De Luca M, Esposito B, Filograna MR, Franceschi A, Galli L, Garazzino S, Gemmi F, Gres E, Lancella L, Liberati C, Lo Vecchio A, Lo Giudice M, Marseglia G, Martelli G, Mengato D, Mercadante S, Meschiari M, Miraglia del Giudice M, Montagnani C, Muggeo P, Nicolini G, Nobili S, Pea F, Pedrotti D, Reggiani L, Sambri V, Sanguinetti M, Santiloni A, Silvani MC, Vatiero L, Zama D, Zampogna S, Zanai R, Esposito S.

Published in: Italian Journal of Pediatrics

Changes in body mass index in children and adolescents living with HIV in Europe and Thailand starting dolutegravir 

2025

Authors: Edgar K, The Epidemiology of Pregnancy and Paediatric Infections International Cohort Collaboration (EPPICC) study group

Published in: Open Forum Infectious Diseases

Mpox-related hospitalization and morbidity in people living with HIV and PrEP users: results from the European MASH-1 cohort study

2025

Authors: Nicoló Girometti on behalf of the MASH-1 study group.

Presented at: European AIDS Conference (EACS) 2025

Effectiveness and safety of tenofovir alafenamide fumarate–based therapy compared to tenofovir disoproxil fumarate- and abacavir-based therapy in children and young people living with HIV in Europe

2025

Authors: Chappell E, The European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC) Study Group

Published in: International Journal of Antimicrobial Agents

Antifungal Prescribing in European Pediatric Intensive Care Units: Results of a multinational 3-month weekly point-prevalence survey

2025

Authors: Chorafa E, Iosifidis E, Alkhaaldi AA, Arias A, Cetin BS, De Luca M, Emonts M, Ferreras-Antolin L, Ghimenton-Walters E, Grasa CD, Groll AH, Herrera-Castillo L, Lehrnbecher T, Manzanares A, Masjosthusmann K, Melendo S, Mendoza-Palomar N, Paulus S, Rincón-López E, Romani L, Sdougka M, Solopova G, Strenger V, Tedford K, Tzika C, Warris A, Zsigmond B, Roilides E.

Published in: Journal of the Pediatric Infectious Diseases Society

Once-daily dolutegravir/lamivudine fixed-dose formulations in children living with HIV: a pharmacokinetic and safety sub-study nested in the open-label, multicentre, randomised, non-inferiority D3/PENTA 21 trial

2025

Authors: Bevers LAH, Toledo G, Kisekka M, Kaudha E, Ahimbisibwe GM, Deprez I, Arumugan T, Variava E, Violari A, White I, Bbuye D, Nanduudu A, Mulwanyi E, Amuge P, Rutebarika DA, Kekitiinwa A, Kityo C, Musoke P, Archary M, Boles J, Thomason MJ, de Wildt SN, Giaquinto C, Colbers A, Burger DM, Buchanan AM, Chan MK, Jacobs TG, Turkova A on behalf of the D3 TRIAL TEAM

Published in: eBioMedicine

Representations of mpox by healthcare professionals and scientists on TikTok: a qualitative analysis of TikTok content

2025

Authors: Nicholls EJ, Le Prevost M, Gomes W, Witzel TC, Bilardi D, Denford S, May T, Tariq S.

Published in: Journal of Medical Internet Research

Long COVID and post-viral fatigue syndrome recorded in children and young people in England primary care, 2006-2022

2025

Authors: Raveendran V, Thorne C, Jackson C, Hardelid P.

Presented at: Administrative Data Research UK (ADR UK) Conference

Impact of the COVID-19 pandemic and the introduction of mRNA vaccines against COVID-19 infection on uptake of childhood vaccines in Norway

2025

Authors: Trinh NTH, Lupattelli A.

Presented at: European Perinatal and Paediatric Epidemiology Conference (EPPEC)

Lessons from the European Mpox Outbreak: Strengthening Cohort Research for Future Pandemic Preparedness

2025

Authors: Visentin A, Nazeri A, Peñalvo JL, Gorska A, Davis RJ, Flett RL, Simensen VC, Langeland N, Gaday Q, Mirandola M, Mazzotta V, Nguyen LBL, Mothe B, Van Dijck C, Meyerhans A, Boesecke C, Giaquinto C, Judd A, Tacconelli E.

Published in: Clinical Microbiology and Infection

The prevalence and seasonal distribution of respiratory viruses, including SARS-CoV-2, in South African children with respiratory tract infections

2025

Authors: McGregor S, Claasen M, Barday M-A, van Niekerk M, Redfern A, Verhagen LM, Rabie H, van der Zalm MM, Hulsman C.

Presented at: Stellenbosch University Academic Year Day

Diarrhoeal admissions among children aged <5 years in public sector facilities in Western Cape Province, South Africa, before and during the COVID-19 pandemic (2019-2021)

2025

Authors: Kehoe K, Morden E, Zinyakatira N, Heekes A, Jones HE, Walter SR, Jacobs T, Murray J, Buys H, Eley B, Redaniel T, Davies M-A.

Published in: South African Medical Journal

Nonparametric serial interval estimation with uniform mixtures

2025

Authors: Gressani O, Hens N.

Published in: PLOS Computational Biology

Adolescents in phase 3 HIV clinical trials

2025

Authors: Foster C, Ruel T, Ford D, Turner RM, Archary M, Rojo P, Gibb D; Penta-IMPAACT.

Published in: The Lancet Child & Adolescent Health

Research gaps for children who are HIV-exposed but uninfected: outcomes of a research prioritisation workshop

2025

Authors: Wedderburn CJ, Evans C, Abrams EJ, Bamford A, Bekker A, Bunders MJ, Epalza C, Foster C, Frigati L, Goetghebuer T, John-Stewart G, Kahlert CR, Moraleda C, Musiime V, Namiba A, Nastouli E, Njuguna I, Pahwa SG, Rabie H, Sainz T, Serghides L, Shibemba M, Tsondai P, Powis K, Thorne C, Prendergast AJ.

Published in: The Lancet HIV

Weight gain on tenofovir alafenamide fumarate‐based therapy compared to tenofovir disoproxil fumarate‐ and abacavir‐based therapy in children and young people living with HIV in Europe

2025

Authors: The European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC) Study Group

Published in: HIV Medicine

Mortality rates and associated factors among people living with perinatally acquired HIV in Europe and Thailand

2025

Authors: O’Rourke J, Chappell E, Collins IJ, Crichton S, Ene L, Le Coeur S, Le Prevost M, Marques L, Naver L, Noguera-Julian A, Pluta M, Prime K, Ramos JT, Spoulou V, van Aerde K, Trickey A, Judd A, on behalf of the Epidemiology of Pregnancy and Paediatric Infections International Cohort Collaboration (EPPICC).

Presented at: International Workshop on Pediatrics and HIV

Developing and streamlining clinical trial services to support pediatric drug development across 21 countries in Europe: insights from the conect4children (c4c) network

2025

Authors: Attar S, Figueiras FP, Peacock C, Wohlfahrt H, Hüsken BCP, Andrews S, Lepola P, Patton M, Hankard R, Halil E, Soares FP, Tan LK, Fernandes RM, Turner MA.

Published in: Frontiers in Medicine

The route to financial sustainability of a large Public Private Partnership—the example of the clinical trial network conect4children (c4c)

2025

Authors: Paumard L, Hildebrand H, Engel M, Lepola P, Montero E, Tennigkeit F, Rosenmöller M

Published in: Frontiers in Medicine

Growth trajectories before and after switching to dolutegravir in children living with HIV in the ODYSSEY trial

2025

Authors: Chan MK, Crichton S, Mujuru HA, Kekitiinwa AR, Lugemwa A, Kityo CM, Ahimbisibwe GM, Variava E, Violari A, Cotton M, Archary M, Cressey TR, Puthanakit T, Bandi S, Bwakura-Dangarembizi M, Bbuye D, Atwine L, Kaudha E, White E, Giaquinto C, Rojo P, Gibb DM, Turkova A, Ford D, and the ODYSSEY Trial Team

Presented at: International workshop on pediatrics and HIV

Pregnancies among adolescents and young women on dolutegravir vs standard-of-care in the ODYSSEY trial and effects of the dolutegravir neural tube defect safety alert

2025

Authors: Ahimbisibwe G, Wyncoll J, Mngqibisa R, White E, Bwakura-Dangarembizi M, Kekitiinwa AR, Lugemwa A, Kityo CM, Variava E, Liberty A, Kataike H, Ngampiyaskul C, Cotton MF, Riault Y, Archary M, Smit T, Puthanakit T, Shakeshaft C, Nhema R, Bbuye D, Atwine L, Kaudha E, Giaquinto C, Rojo P, Bamford A, Gibb DM, Turkova A, Ford D, Musoke P, and the ODYSSEY Trial Team

Presented at: International Workshop on Pediatrics and HIV

Growth outcomes in children living with HIV in Europe and Thailand before and after starting dolutegravir

2025

Authors: Edgar K, Scott K, Castro H, O’Rourke J, Ene L, Galli L, Goetghebuer T, Henegar C, Hoffmann TU, Koenigs C, Marczyńska M, Naver L, Noguera-Julian A, Paioni P, Puthanakit T, Ramos Amador JT, Spoulou V, Tantawarak N, Vannappagari V, Volokha A, Turkova A, Judd A, Collins IJ, Crichton S, on behalf of the Epidemiology of Pregnancy and Paediatric Infections International Cohort Collaboration (EPPICC)

Presented at: International Workshop on Pedatrics and HIV

Predictors of treatment failure in children living with HIV starting first-line antiretroviral therapy in the ODYSSEY trial

2025

Authors: Wyncoll J, Archary M, Kamolrattana R, Mujuru HA, Kekitiinwa AR, Violari A, Na-Rajsima S, Lugemwa A, Variava E, Cotton M, Kityo CM, Puthanakit T, Königs C, Behuhuma O, Welch S, Saïdi Y, Marques L, Ahimbisibwe GM, Holden L, Giaquinto C, Rojo P, Gibb DM, Turkova A, White E, Ford D, and the ODYSSEY Trial Team

Presented at: IAS 2025

Causes of death among sub-Saharan African infants living with HIV and hospitalised with severe pneumonia, using minimally invasive autopsies in the EMPIRICAL trial

2025

Authors: Moraleda C, Madrid L, Rakislova N, Buck WC, Sacarlal J, Chabala C, Hurtado JC, Cassia U, Domínguez-Rodríguez S, Carrilho C, Varo R, Torres-Fernandez D, Ballesteros A, Tagarro A, Fernandez-Luis S, Fernandes F, Tembo J, Namuziya N, Navero J, Ordi J, Tivane A, Martins S, Cossa A, Rojo P, Bassat Q

Presented at: The International Workshop on Pediatrics and HIV

Viral Suppression, Viral Failure, and Safety Outcomes in Children and Adolescents With Human Immunodeficiency Virus (HIV) on Dolutegravir in Europe and Thailand

2025

Authors: Scott K, O’Rourke J, Jackson C, Ene L, Galli L, Goetghebuer T, Henegar C, Königs C, Marczyńska M, Naver L, Noguera-Julian A, Paioni P, Ramos JT, Smith B, Songtaweesin WN, Spoulou V, Tantawarak N, Turkova A, Vannappagari V, Volokha A, Bamford A, Castro H, Chappell E, Dalla Valle G, Foster C, Guillén Martín S, Prieto Tato LM, Puthanakit T, Sherstiuk H, Shkurka I, Soeria-Atmadja S, Judd A, Crichton S, Collins IJ

Published in: Clinical Infectious Diseases

Are children and adolescents living with HIV in Europe and South Africa at higher risk of SARS-CoV-2 and poor COVID-19 outcomes?

2025

Authors: European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC) SARS-CoV-2 Antibody Study Group

Published in: Epidemiology and Infections

Outcomes After Prenatal Exposure to Raltegravir-Containing Antiretroviral Therapy: A Multicohort European Study

2025

Authors: Sconza R, Fernandes G, Bailey H, Peters H, Prieto Tato LM, Illán Ramos M, Aebi-Popp K, Kahlert C, Gamell AM, Frick A, Ene L, Samarina A, Thorne C; European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC)

Published in: Journal of Acquired Immune Deficiency Syndrome

Effect of Empirical Treatment with Valganciclovir on Mortality in Infants with Severe HIV -associated Pneumonia: a multicenter, open-label, randomized factorial clinical trial

2025

Authors: C. Moraleda, A. Tagarro, S. Domínguez-Rodríguez, W.C. Buck, V. Musiime, H. Mujuru, C. Chabala, P.-Y. Iroh-Tam, T. Mvalo, J. Bramugy, L. Madrid, J. Sacarlal, A. Passanduca, H. Aanyu, A. Tagoola, C. Mutata, B. Nduna, L. Ghambi, C. Chawinga, M. Bates, S. Fernández-Luis, M. Sidat, U. Cassia, D. Nansera, M. Bwakura-Dangarembizi, N. Namuziya, F. Nkongho, J. Tembo, Á. Ballesteros, L. Manukyan, O. Marcy, T. Jacobs, D. Burger, Q. Bassat, V. Leroy, A. Nardone, P. Rojo, Empirical Clinical Trial Group.

Presented at: IAS 2025

Effectiveness and safety of dolutegravir (DTG) in infants and children aged under 12-years at start of DTG in Europe and Thailand

2025

Authors: Scott K, Castro H, O’Rourke J, Edgar K, Ene L, Galli L, Goetghebuer T, Henegar C, Hoffmann UT, Königs C, Marczyńska M, Naver L, Noguera-Julian A, Paioni P, Puthanakit T, Ramos Amador JT, Spoulou V, Tantawarak N, Vannappagari V, Volokha A, Turkova A, Judd A, Collins IJ, Crichton S, on behalf of the Epidemiology of Pregnancy and Paediatric Infections International Cohort Collaboration (EPPICC)

Presented at: International Workshop on HIV and Pediatrics

Empirical treatment against tuberculosis in infants with HIV-associated pneumonia: a multicenter, open label, randomized factorial clinical trial.

2025

Authors: Tagarro A, Moraleda1 C, Dominguez-Rodríguez S, Buck C, Musiime V, Mujuru H,  Chabala C, Iroh Tam YP, Mvalo T, Bramugy J, Madrid L, Sacarlal J, Passanduca A, Aanyu H,  Tagoola A, Mutata C, Nduna B, Ghambi L, Chawinga C, Bates M, Fernández-Luis S, Cassia U,  Sidat M, Nansera D, Bwakura-Dangarembizi M, Namuziya N, Nkongho F, Tembo J, Ballesteros A,  Manukyan L, Marcy O, Jacobs T, Burger D, Bassat Q, Leroy V, Poey N, Nardone A, Rojo P, Empirical Clinical Trial Group

Presented at: IAS 2025

Pharmacokinetic modeling to support WHO-weight band dosing of the new pediatric Darunavir/ritonavir (120/20 mg) fixed-dose combination tablet for children

2025

Authors: Abdalla S, Lallemant M, Compagnucci A, Nardone A, Giaquinto C, Gibb D, Chabala C, Burger D, Hirt D, Cressey RT for the UNIVERSAl-2 Team

Presented at: IAS 2025

Challenges of recruiting children living with HIV failing antiretroviral therapy into a trial for participants with multi-class drug resistance into a prospective clinical trial

2025

Authors: Grasa C, Archary M, Frigati L, Violari A, Patel F, Strehlau R, Camacho-Gonzalex A, Maboa R, Rakhmanina N, Salvadori N, Nardone A, Than-In-At K,Koblansky A, Thakka N, Tan L, Giaquinto C, Cressy TR, Rojo P

Presented at: IAS and International Workshop on HIV and Pediatrics

Characteristics of antiretroviral resistance in participants from the SHIELD trial: a pharmacokinetic and safety study evaluating fostemsavir in children and adolescents living with multi-drug resistant HIV

2025

Authors: Archary M, Frigati L, Violari A, Patel F, Strehlau R, Camacho-Gonzalez A, Maboa R , Rakhmanina N, Grasa C, Salvadori N, Nardone A, Than-In-At K, Parry C, Keegan M, López Varela E, Giaquinto C, Cressey TR, Rojo P

Presented at: IAS

Efficacy of second-line dolutegravir- versus boosted protease inhibitor-based ART in children and adolescents living with HIV at 96 and 144 weeks: pooled analysis of the ODYSSEY and CHAPAS-4 trials

2025

Presented by: Amuge P on behalf of the CHAPAS-4 trial, ODYSSEY trial and UNIVERSAL teams

Presented at: International Workshop on HIV and Pediatrics

Factors associated with HIV-1 DNA dynamics in early treated childrenwith perinatal HIV

2025

Presented by: Tagarro A, Reddy K, Molechan C, Dominguez-Rodriguez S, Smith T, Spyer M, Barnabas S, Lain M, Otwombe K, Nhampossa T, Maiga A, Rojo P, Giaquinto C, Rossi P, Ndung’u T, on behalf of the EPIICAL Consortium

Presented at: IAS (Oral presentation), IAS (Poster presentation), International Workshop on HIV and Pediatrics, Towards HIV Cure pre-meeting

“Four queer men in the UK have contracted monkeypox”: Grammar, agency, and stigma in media reporting of mpox outbreaks

2025

Presented by: Malory B, on behalf of the VERDIQual team

Presented at: Corpus Linguistics Conference

British news media representations of the 2022 and 2024 mpox outbreaks: A corpus-assisted study

2025

Authors: Malory B, Le Prevost M, Nicholls EJ, Bilardi D, Tariq S.

Presented at: Corpus Linguistics Conference

“That took me back to HIV in the ’90s”: Community reflections on public health responses to the 2022 mpox outbreak

2025

Authors: Witney T, Nicholls EJ, Le Prevost M, Gharib Y, Tariq S, on behalf of the VERDIQual team

Presented at: BASHH Annual Conference

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