Publications

Strengthening mpox vaccine trials through community engagement: Findings from workshops with women, healthcare professionals, and community leaders in Boende, Democratic Republic of the Congo (DRC)

2025

Presented by: Le Prevost M, Bikioli F, on behalf of the PregInPoxVac social science team 

Presented at: EDCTP Forum

Tolerability and Acceptability of Dispersible Oral Tablets of Amoxicillin and Co-Amoxiclav in African Children Hospitalized with Severe Pneumonia: Results from the PediCAP trial

2025

Presented by: Sidat MM, on behalf of the PediCAP trial team

Presented at: INSPiRED

Antifungal Use in Immunocompromised Children in Europe: A 12-Week Multicenter Weekly Point Prevalence Survey (CALYPSO)

2025

Authors: Chorafa E, Iosifidis E, Oletto A, Warris A, Castagnola E, Bruggemann R, Groll AH, Lehrnbecher T, Antolin LF, Mesini A, Alkhaaldi AA, Baquero-Artigao F, Cetin BS, Ebrahimi-Fakhari D, Emonts M, Esposito S, Fainardi V, Ghimenton-Walters E, Gijón M, Guerrero AG, Grasa CD, Kairiene I, Kildonaviciute K, Kourti M, Manzanares A, Mendoza-Palomar N, Noni M, Papakonstantinou E, Paulus S, Perwein T, Rascon J, Rincón-López E, Soler-Palacin P, Solopova G, Spoulou V, Strenger V, Tedford K, Tzika C, Zsigmond B, Roilides E.

Published in: Journal of pediatric hematology/oncology

 

Brain MRI and neurocognitive characteristics of children and adolescents living with HIV

2025

Authors: Martín-Bejarano García M, Jackson C, Okhonskaia L, Voronin E, Rozenberg V, Titova MA, Kovalenko T, Wedderburn C, Collins IJ, Crichton S, Velo Higueras C, Salvador E, González-Tomé MI, Turkova A, Ramos-Amador JT, Martinez de Aragón A.

Published in: Child Neuropsychology

ESPID Clinical Practice Guideline: Management of paediatric community-acquired pneumonia

2025

Presented by: Brigadoi G, Ambroggio L

Presented at: ESPID 2025

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Transforming trends: the changing landscape of infections in children over eight years

2025

Authors: Brigadoi G, Gres E, Zin A, Francaviglia G, Levinte E, Chiusaroli L, Rossin S, Chiariotti D, Ferraris G, Barbieri E, Liberati C, Giaquinto C, Bressan S, Donà D.

Presented at: ESPID 2025

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Mucosal immunity matters: salivary antibodies and cytokines are associated with disease severity in South African children hospitalized with acute respiratory infections

2025

Presented by: Geert van Weelden, on behalf of the VERDI consortium

Presented at: ESPID 2025

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The effect of pre-existing coronavirus antibodies on SARS-CoV-2 infection outcomes in exposed household members

2025

Authors: Westerhof I, Sikkema R, Rozhnova G, van Beek J, Koopmans M, Bruijning-Verhagen P.

Presented at: WEON Conference

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SARS-CoV-2 Infection Incidence and Severity in Immunocompromised Children: A Population-Based Study in Italy and Norway

2025

Presented by: Costanza di Chiara on behalf of the VERDI consortium

Presented at: “Best of ESPID” session – ESPID 2025

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EVOLUTION OF THE RESERVOIR IN EARLY TREATED CHILDREN WITH HIV-1 IN SUB-SAHARAN AFRICA

2025

Authors: Tagarro A, Reddy K, Barnabas S, Dominguez-Rodriguez S, Lain MG, Rojo P, Palma P, Ndung’u T, Spyer M, Nhampossa T, Otwombe K, Maiga A, Giaquinto C, Rossi P, on behalf of the EPIICAL Consortium

Presented at: ESPID 2025

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1 out of 20 children with HIV can achieve undetectable HIV-1 reservoir in Africa

2025

Authors: Tagarro A, Reddy K, Dominguez S, Barnabas S, Rojo P, Lain MG, Palma P, Cotugno N, Nastuoli E, Giaquinto C, N’Dungu T, Rossi P, on behalf of the EPIICAL Consortium

Presented at: ESPID 2025

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BREATHER plus clinical trial design: A randomised non-inferiority trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily ART in virologically suppressed adolescents living with HIV aged 12 to <20 years in sub-Saharan Africa

2025

Authors: Katongole F, Arumugam T, Jennings A, Mutata C, Ssebunya P, Wamboi C, Green A, Dangarembizi MB, Mutuluuza CK, Siika A, Archary M, Jafta L, Namukwaya S, Seeley J, Mugerwa H, Walker S, Apoto N, Thomason MJ, Ford D, Pett SL, Kekitiinwa AR.

Published in: Contemporary Clinical Trials

Clinical characteristics of COVID-19 in children and adolescents: insights from an Italian paediatric cohort using a machine-learning approach

2025

Authors: Fiandrino S, Donà D, Giaquinto C, Poletti P, Tira MD, Paolotti D, Di Chiara C.

Published in: BMC Public Health

Engagement and satisfaction of healthcare workers with online training in infection prevention, control, and antimicrobial stewardship: insights from the TEAM-COACH project

2025

Authors: Brigadoi G, Kopsidas I, Barbieri E, Villaverde S, Goycochea W, Bason M, Kousi D, Arias A, Aboza M, Moutou A, Dona’ D, Neth O, Cantarutti L, Gianquinto C, Gâchet A, Ballesteros Á, Rojo P, Epalza C; TEAM-COACH working group.

Presented at: ESPID 2025

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Clinical practice indicators for IPC and AMS in the pediatric population before and after participation in the pilot phase of a training project using an electronic tool (TEAM-COACH project)

2025

Presented by: Serena Villaverde on behalf of the TEAM-COACH Consortium

Presented at: ESPID 2025

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Drivers of quasispecies development in SARS-CoV-2 and implications for emergent variants and COVID-19

2025

Authors: Smet M, Berkell M, Górska A, Tacconelli E, Kumar-Singh S, Malhotra-Kumar S.

Published in: Virology

The Potential to Leverage Real-World Data for Pediatric Clinical Trials: A Proof-of-Concept Study

2025

Authors: Declerck J, Lee J, Sen A, Palmeri A, Oostenbrink R, Giannuzzi V, Woodworth S, Malik S, Mahler F, Aurich B, Leary R, Kalra D, Straub V.

Published in: Journal of Medical Internet Research

Interference between respiratory viruses in a cohort of healthy young children; a self-controlled case-series study

2025

Authors: Hauser van Westrhenen E, Junquera Guinovart L, Schuurman R, van Boven M, Bonten M, Bruijning Verhagen P.

Presented at: ESPID 2025

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Effect of restrictions, travelling or school holidays on the incidence of COVID-19 in children and adults

2025

Authors: Soeorg H, Abroi A, Päll T, Avi R, Sadikova O, Sepp H, Reisberg T, Lutsar I, Huik K.

Presented at: ESPID 2025

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COVID-19 related hospitalizations in Estonian children and adolescents during 5 SARS-CoV-2 variant periods

2025

Authors: Kerna AL, Huik K, Sepp H, Jõgeda EL, Jõgi P, Lutsar I, Soeorg H.

Presented at: ESPID 2025

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Symptomatology of SARS-CoV-2 versus seasonal Coronavirus infection in healthy young children

2025

Authors: Junquera Guinovart LP, Hauser-van Westrhenen SEM, Schuurman R, Bruijning-Verhagen PCJL.

Presented at: ESPID 2025

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Mortality and infection-related outcomes in low birth weight infants receiving Kangaroo Care: a systematic review and meta-analysis

2025

Authors: Minotti C, Jost K, Aghlmandi S, Schlaeppi C, Sieswerda E, Van Werkhoven H, Schulzke S, Bielicki J.

Presented at: ESPID 2025

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Assessing the quality and impact of the PentaTr@ining programme on clinical management of paediatric HIV and other congenital infections

2025

Authors: Di Chiara C, Venturini E, Delory T, Jacobs T, Nyirenda M, Bajura V, McEneaney P, Kopsidas I, Lyall H, Welch S.

Presented at: ESPID 2025

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Pediatricians’ knowledge, attitudes, and perceived barriers to RSV immunization in Europe

2025

Authors: Di Chiara C, Piché-Renaud P-P, Rigamonti V, Cantarutti A, Calvo C, Rivero Calle I, Soriano-Arandes A, Giaquinto C, Cantarutti L, Donà D, Lo Vecchio A, Hadjipanayis A, Pana ZD, Kopsidas I, Rose A, Tagarro A, Morris SK, on behalf of the Penta Respiratory Infection Working Group.

Presented at: ESPID 2025

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All-cause mortality and infection-related outcomes of hospital-initiated kangaroo care versus conventional neonatal care for low-birthweight infants: a systematic review and meta-analysis

2025

Authors: Minotti C, Jost K, Aghlmandi S, Schlaeppi C, Sieswerda E, Van Werkhoven H, Schulzke S, Bielicki J.

Published in: The Lancet Child & Adolescent Health

Empowering young voices in clinical research: co-creation of an educational video to support informed assent

2025

Authors: Kamphuis AEM, Jafta LP, Jacobs TG, on behalf of the Penta Youth Trials Board

Published in: The Lancet Child & Adolescent Health

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Antibiotic use attributable to RSV infections during infancy—an international prospective birth cohort study

2025

Authors: Hak SF, Venekamp RP, Billard M-N, Cianci D, van Houten MA, Pollard AJ, Heikkinen T, Cunningham S, Millar M, Martinon-Torres F, Dacosta-Urbieta A, Bont LJ, Wildenbeest JG; on behalf of the PROMISE Investigators.

Published in: Journal of Antimicrobial Chemotherapy

Impact of co-infection with SARS-CoV-2 and other respiratory viruses on illness: Pooled analyses of 11 COVID-19 cohorts

2025

Authors: de Hoog MLA, Hauser-van Westrhenen ESEM, Winkel AMAM, de Jong MD, van Houten MA, van Lelyveld SFL, Eggink D, Euser S, Duijts L, Wildenbeest JG, Schuurman R, van de Wijgert JHHM, Ieven M, Loens K, van der Velden AW, Bonten MJM, Goossens H, Bruijning-Verhagen PCJL.

Published in: Journal of Infection

Statistical analysis plan for the “empirical treatment against cytomegalovirus and tuberculosis in HIV-infected infants with severe pneumonia” clinical trial

2025

Authors: Domínguez-Rodríguez S, Lora D, Tagarro A, Moraleda C, Ballesteros Á, Madrid L, Manukyan L, Marcy O, Leroy V, Nardone A, Burger D, Bassat Q, Bates M, Moh R, Iroh Tam P-Y, Mvalo T, Magallhaes J, Buck WC, Sacarlal J, Mussime V, Chabala C, Mujuru HA, Rojo P on behalf of the EMPIRICAL group

Published in: Trials

Assessment of the steady-state drug-drug interactions between dolutegravir and ritonavir-boosted darunavir in adolescents

2025

Authors: Abdalla S, Compagnucci A, Bamford A, Chan MK, Ramos JT, Riault Y, Saidi Y, Constant V, Nguyen T, Giaquinto C, Tréluyer JM, Cressey TR, Hirt D, the SMILE Study Group, Bologna R, Reliquet V, Elenga N, Pavia-Ruz N, et al

Published in: AIDS

Whole genome sequencing analysis of SARS-CoV-2 household transmission in Chiang Mai, Thailand during 2022–2024

2025

Authors: Inmonthian P, Suebtam P, Sripan P, Wangsaeng N, Kham-Kjing N, Pinasu A, Kohklang N, Collins J, Spyer M, Angkurawaranon C, Ngo-Giang-Huong N, Khamduang W.

Presented at: 32nd International Dynamics & Evolution of Human Viruses conference

Long-term neuropsychiatric and neuropsychological impact of the pandemic in Italian COVID-19 family clusters, including children and parents

2025

Authors: Di Chiara C, Ferrarese M, Boracchini R, Cantarutti A, Tibaldo AL, Stefanni C, Donà D, De Pieri M, Raffagnato A, Tascini B, Miscioscia M, Occhino F, Giaquinto C, Gatta M.

Published in: PLoS One

“Common sense is hard work” but benefits from persistent collaboration: Lessons learnt from the development of The Collaborative Network for European Clinical Trials for Children (c4c) to support the conduct of paediatric clinical trials of medicines

2025

Authors: Attar S, Peacock C, Wan M, Halil E, Bickerstaff C, Tan L, Bhatti H, Fernandes RM, Hankard R, Turner MA.

Published in: Contemporary Clinical Trials Communications

Viral suppression, viral failure and safety outcomes in children and adolescents living with HIV on dolutegravir in Europe and Thailand 

2025

Authors: Scott K, O’Rourke J, Jackson C, Ene L, Galli L, Goetghebuer T, Henegar C, Königs C, Marczyńska M, Naver L, Noguera-Julian A, Paioni P, Ramos JT, Smith B, Songtaweesin WN, Spoulou V, Tantawarak N, Turkova A, Vannappagari V, et al

Published in: Clinical Infectious Diseases

Penta Network: State-of-the-Art Research in Pediatric Human Immunodeficiency Virus

2025

Authors: Rojo P, Moraleda C, Giaquinto C

Published in: Clinics in Perinatology

Clinical presentation and epidemiological assessment of confirmed human mpox cases in DR Congo: a surveillance-based observational study

2025

Authors: Malembi E, Escrig-Sarreta R, Ntumba J, Beiras CG, Shongo R, Bengehya J, Nselaka C, Pukuta E, Mukadi-Bamuleka D, Mulopo-Mukanya N, Leng X, Pérez-Mañá C, Galván-Casas C, Muñoz S, Bilembo-Kitwanda S, Kitha P, Maketa V, Mitashi P, Abedi A, Nsio J, Ahuka-Mundeke S, Mbala-Kingebeni P, Muyembe JJ, Marks M, Muhindo-Mavoko H, Mitjà O; MOTION-DRC Working Group.

Published in: The Lancet

Exploring influenza vaccination determinants through digital participatory surveillance

2025

Authors: Kelley K, Gozzi N, Mazzoli M, Paolotti D.

Published in: BMC Public Health

Risk factors for resistant bacterial colonisation in 24 European neonatal units in the NeoIPC project

2025

Authors: Cook A, Berkell M, Malhotra-Kumar S, Bielicki J, on behalf of the NeoIPC Consortium.

Presented at: ESCMID 2025

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A simulation study of antimicrobial resistance carriage in neonatal intensive care units: implications for cluster-randomised trials

2025

Authors: van Werkhoven CH, Berkell M, Cook A, Sieswerda E, Malhotra-Kumar S, Bielicki JA, by the NeoIPC consortium

Presented at: ESCMID 2025

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Dynamics of gastrointestinal colonisation by antibiotic-resistant bacteria in high-risk infants in Swiss and Greek neonatal intensive care units

2025

Authors: Braspenning A, Timbermont L, Van Heirstraeten L, Berkell M, Cook A, Sieswerda E, van Werkhoven CH, Bielicki JA, Malhotra-Kumar S; on behalf of the NeoIPC Consortium.

Presented at: ESCMID 2025

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Pool-testing for surveillance of key bacterial resistance genes in infants’ stools

2025

Authors: Minotti C, Bräm D, Cook A, Berkell M, Bielicki J; and the NeoIPC Consortium

Presented at: ESCMID 2025

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The effect of pre-existing coronavirus antibodies on SARS-CoV-2 infection outcomes in exposed household members

2025

Authors: Westerhof I, Sikkema R, Rozhnova G, van Beek J, Koopmans M, Bruijning-Verhagen P.

Published in: The Journal of Infectious Diseases

Advancing European paediatric research – the contribution of the Innovative Health Initiative

2025

Authors: Seigneuret N

Published in: Frontiers in Medicine

IPNA consensus definitions for clinical trial outcomes in steroid-resistant nephrotic syndrome

2025

Authors: Hari P, Khandelwal P, Boyer O, Bhimma R, Cano F, Christian M, Duzova A, Iijima K, Kang HG, Qian S, Safouh H, Samuels S, Smoyer WE, Vivarelli M, Bagga A, Schaefer F; IPNA Best Practices and Standards Committee and c4c Pediatric Nephrology Expert Working Group.

Published in: Pediatric Nephrology

Infectivity in full-term placenta of Zika viruses with different lipid profiles

2025

Authors: Mazzetto E, Bortolami A, Bovo D, Stocchero M, Mazzacan E, Napolitan A, Panzarin V, Tran MR, Zamperin G, Milani A, Fortin A, Bigolaro M, Pirillo P, Pagliari M, Zanardello C, Giordano G, Gervasi MT, Baraldi E, Terregino C, Giaquinto C, Bonfante F.

Published in: Virus Research

Clinical findings and neurodevelopmental outcome in Jamaican children with suspected congenital Zika syndrome

2025

Authors: Melbourne-Chambers, R., Palmer, P., Brown, Y., James-Powell, T., Tapper, J., Mowatt, L., … Thorne, C. (2025).

Published in: Paediatrics and International Child Health

Immune Profile of Children With Post-COVID-19 Cardiac Contractility Alterations: a Prospective Study

2025

Authors: Di Chiara C, Cantarutti A, Sabatino J, Sirico D, Bonfante F, Le Prevost M, Buonsenso D, Donà D, De Rossi A, Giaquinto C, Petrara MR, Di Salvo G.

Presented at: CROI 2025

Infants with HIV starting ART withing 4 months of age can achieve sustained undetectable HIV-1 DNA

2025

Authors: Tagarro A, Reddy K, Dominguez-Rodriguez S, Rojo P, Barnabas S, Otwombe K, Lain MG, Maiga A, Kuhn L, Palma P, Cotugno N, Nastuoli E, Giaquinto C, Ndung’u T, Rossi P; on behalf of the EPIICAL Consortium

Presented at: CROI

Assessing the role of children in the COVID-19 pandemic in Belgium using perturbation analysis

2025

Authors: Angeli L, Caetano CP, Franco N, Coletti P, Faes C, Molenberghs G, Beutels P, Abrams S, Willem L, Hens N.

Published in: Nature Communications

Clinical impact of circulating biomarkers in prediction of adverse cardiac events in patients with congenital heart disease. A systematic review

2025

Authors: van Genuchten WJ, Averesch H, van Dieren QM, Bonnet D, Odermarsky M, Beghetti M, Roos-Hesselink JW, Reinhardt Z, Male C, Naumburg E, Boersma E, De Wolf D, Helbing WA; also on behalf of Cardiology Expert Group of the connect4children (c4c) network.

Published in: International Journal of Cardiology

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