Publications

The impact of underreported infections on vaccine effectiveness estimates derived from retrospective cohort studies

2024

Authors: Sacco C, Manica M, Marziano V, Fabiani M, Mateo-Urdiales A, Guzzetta G, Merler S, Pezzotti P.

Published in: International Journal of Epidemiology

COVID-19 vaccine uptake and effectiveness by time since vaccination in the Western Cape province, South Africa: An observational cohort study during 2020-2022

2024

Authors: Kassanjee R, Davies M-A, Heekes A, Mahomed H, Hawkridge AJ, Morden E, Jacobs T, Cohen C, Moultrie H, Lessells RJ, et al.

Published in: Vaccines

Reducing Neonatal Severe Infection and Resistance Through Optimised Skin-To-Skin Contact (KC – Kangaroo Care) Using Pragmatic Data Collection Approaches

2024

Authors: Djukic F, Aislinn A, Vitale E, Martin J, Minotti C, Schlaeppi C, Bielicki J.

Presented at: ESPID 2024

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Risk of SARS-CoV-2 Reinfection in Children within the 12 Months Following Mild COVID-19: Insights from a Survey Study

2024

Authors: Di Chiara C, Boracchini R, Cantarutti A, Kakkar F, Oletto A, Padoan A, Donà D, Giaquinto C.

Presented at: ESPID 2024

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Previous experience and motivation of healthcare workers for training in infection prevention and control and antimicrobial stewardship (the Team-COACH project)

2024

Authors: Epalza C, Villaverde S, Tsopela CG, Brigadoi G, Aboza M, Barbieri E, Bason M, Poulimeneas D,Donà D, Goycochea W, Cantarutti L, Kopsidas I, Neth O, Gâchet A, Ballesteros A, Dominguez S, Manukyan L, Rojo P

Presented at: ESPID 2024

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Impact of In-Utero Exposure to Maternal SARS-CoV-2 Infection on Children’s Hospital Admission Rates: National Birth Cohort Study in England

2024

Authors: Liu M, Wijlaars L, Judd A, Jackson C, Thorne C, Collins J, Hardelid P.

Presented at: ESPID 2024

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SARS-CoV-2 Infection Incidence and Severity in Immunocompromised Children: A Population-Based Study in Italy and Norway

2024

Authors: Di Chiara C, Trinh N, Lupattelli A, Le Prevost M, Boracchini R, Giugni A, Barbieri E, Giaquinto C, Donà D, Cantarutti A.

Presented at: ESPID 2024

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High maximum incidence of SARS-CoV-2 Delta and Omicron variants in children was associated with low cumulative infection rate and vaccination coverage in Estonia

2024

Authors: Soeorg H, Abroi A, Päll T, Avi R, Lutsar I, Huik K.

Presented at: ESPID 2024

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HIV-1 drug resistance dynamics in the EARTH cohort: a mother-infant pair perspective

2024

Authors: Torres-Fernandez D, Domínguez-Rodríguez S, Fernández-Luis S, Nhampossa T, Lopez-Varela E, Naniche D, Lain GM, Ismael N, Spyer JM, Byott M, Nastouli E, Rossi P, Rojo P, Tagarro A on behalf of the EPIICAL Consortium.

Presented at: ESPID 2024

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HIV-1 drug resistance dynamics in the EARTH cohort: a mother-infant pair perspective

2024

Authors: Torres-Fernandez D, Domínguez-Rodríguez S, Fernández-Luis S, Nhampossa T, Lopez-Varela E, Naniche D, Lain GM, Ismael N, Spyer JM, Byott M, Nastouli E, Rossi P, Rojo P, Tagarro A on behalf of the EPIICAL Consortium.

Presented at: ESPID 2024

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High mortality following early initiation of antiretroviral therapy in infants living with HIV from three African countries

2024

Authors: Tagarro A, Domínguez-Rodríguez S, Cotton M, Otwombe K, Klein N, Lain GM, Nhampossa T, Maiga IA, Barnabas S, Vaz P, Violari A, Fernández-Luis S, Behuhuma O, Sylla M, López-Varela E, Naniche D, Janse-Van-Rensburg A, Liberty A, Ramsagar N, Smit T, Rojo P et al on behalf of EPIICAL consortium

Published in: eClinical Medicine

Randomised multicentre effectiveness trial of rapid syndromic testing by panel assay in children presenting to European emergency departments with acute respiratory infections—trial protocol for the ADEQUATE Paediatric trial

2024

Type: Protocol

Published in: BMJ Journals

COVID-19 vaccine uptake among children and adolescents in Norway: A comprehensive registry-based cohort study of over 800,000 individuals

2024

Authors: Orangzeb S, Desalegn A, Trinh NTH, Zhao J, Nordeng H, Lupattelli A.

Published in: Vaccine

Prevalence of antibiotic-resistant bacterial colonization in neonatal intensive care in Europe

2024

Authors: Berkell M, Van Heirstraeten L, Cook A, Bielicki J, Malhotra-Kumar S

Presented at: ESCMID Global (ECCMID) 2024

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Unit-level antibiotic resistant bacterial colonisation pressure in 20 neonatal units across Europe

2024

Authors: Cook A, Berkell M, Bram D, on behalf of the NeoIPC Consortium

Presented at: ESCMID Global (ECCMID) 2024

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Early oral step-down to amoxicillin is safe and effective for children hospitalised with severe community-acquired pneumonia: the PediCAP trial

2024

Authors: Musiime V on behalf of the PediCAP trial team

Presented at: ESCMID Global 2024

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Mapping of Data-Sharing Repositories for Paediatric Clinical Research—A Rapid Review

2024

Authors: Felisi M, Bonifazi F, Toma M, Pansieri C, Leary R, Hedley V, Cornet R, Reggiardo G, Landi A, D’Ercole A, Malik S, Nally S, Sen A, Palmeri A, Bonifazi D, Ceci A.

Published in: Data

Joint recommendations on cost calculation and estimation in paediatric clinical trials

2024

Authors: Ahne G, Nagel J, Franz AR, Neubert A, Schachtrup K, Helms S, Klammt S, Schwab M. 

Published in: German Medical Science

The decline of the 2022 Italian mpox epidemic: Role of behavior changes and control strategies

2024

Authors: Guzzetta G, Marziano V, Mammone A, Siddu A, Ferraro F, Caraglia A, Maraglino F, Rezza G, Vespignani A, Longini I, Ajelli M, Merler S.

Published in: Nature Communications

The socioeconomic impact of the COVID-19 lockdown on families affected by childhood respiratory illnesses in Cape Town, South Africa

2024

Authors: Anthony MG, Hoddinott G, Van Niekerk M, Dewandel I, McKenzie C, Bekker C, Rabie H, Redfern A, van der Zalm MM

Published in: PLOS Global Public Health

Lower respiratory tract infection admissions and deaths among children under 5 years in public sector facilities in the Western Cape Province, South Africa, before and during the COVID-19 pandemic (2019 – 2021)

2024

Authors: Kehoe K, Morden E, Zinyakatira N, Heekes A, Jones H, Walter S, Jacobs T, Murray J, Buys H, Redaniel MT, Davies MA.

Published in: South African Medical Journal

SARS-CoV-2 Infection and Hospitalization in Immunocompromised Children: A Population-Based Study

2024

Authors: Di Chiara C, Giugni A, Le Prevost M, Boracchini R, Barbieri E, Lupattelli A, Giaquinto C, Donà D, Cantarutti A.

Presented at: ICAR-CROI Awards for young Italian investigators, March 2024

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Pharmacokinetics of once-daily DTG/3TC FDC in children living with HIV: D3/PENTA21 sub-study

2024

Authors: Bevers HAL, Chan KM, Bbuye D, Kekitiinwa RA, Kityo C, Kaudha E, Ahimbisibwe MG, Arumugam T, Moloantoa T, Boles J, Deprez I, Giaquinto C, Turkova A, Colbers A for the D3/Penta21 trial team

Presented at: CROI 2024

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HIV-1 Reservoir Dynamics in Children With Early Treated, Perinatally-Acquired HIV: Does Sex Matter?

2024

Authors: Reddy K, Molechan C, Dominguez-Rodriguez S, Smith T, Spyer M, Lichterfeld M, Rojo P, Giaquinto C, Rossi P, Palma P, Isaacs M, Cardoso L, Liberty A, Estevao L, Tagarro A, Ndung’u T for EPIICAL

Presented at: CROI 2024

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SARS-CoV-2 Infection and Hospitalization in Immunocompromised Children: A Population-Based Study

2024

Authors: Di Chiara C, Giugni A, Le Prevost M, Boracchini R, Barbieri E, Lupattelli A, Giaquinto C, Donà D, Cantarutti A.

Presented at: CROI 2024

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Risk of SARS-CoV-2 Reinfection in Children Within the 12 Months Following Mild COVID-19: Insights From a Survey Study

2024

Authors: Di Chiara C, Boracchini R, Cantarutti A, Kakkar F, Oletto A, Padoan A, Donà D, Giaquinto C.

Published in: The Pediatric Infectious Disease Journal

Outcomes Following Prenatal Exposure to Raltegravir: A Multi-Cohort European Study

2024

Authors: Sconza R, Fernandes G, Aebi-Popp K, Ene L, Frick A, Gamell A, Ramos IM, Kahlert C, Peters H, Tato PML, Samarina A, Giaquinto C, Thorne C for the EPPICC Pregnancy Study Group

Presented at: CROI 2024

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ODYSSEY 192-week follow-up evidences superior efficacy of DTG for children on first/second-line ART

2024

Authors: Mujuru AH, White E, Kekitiinwa A, Lugemwa A, Kityo C, Musoke P, Cressey RT, Variava E, Violari A, Archery M, Cotton M, Puthanakit T, Rojo P, Turkova A

Presented at: CROI 2024

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Causes of death after early ART in infants living with HIV from 3 sub-Saharan African countries

2024

Authors: Tagarro A, Fernández-Luis S, Dominguez-Rodriguez S, Ballesteros A, Kuhn L, Cotton FM, Giaquinto C, Rossi P, Spyer M, Otwombe K, Behuhuma O, Vaz P, Foster C, Rojo P, for EPIICAL

Presented at: CROI 2024

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An efficient envelope genotypic assay to identify bNab susceptibility in infants with HIV

2024

Authors: Delaney EK, Kearney FM, Bester AP, Coetzee N, Engelbrecht S, Giaquinto C, Rossi P, Barnabas LS, Spyer JM, Litcherfeld M, Tagarro A, Lombard C, Cotton FM, Zyl vUG and EPIICAL Consortium

Presented at: CROI 2024

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1 in 5 sub-Saharan infants switches from undetectable to detectable HIV viral load during follow-up  

2024

Authors: Fernández-Luis S, Dominguez-Rodriguez S, Kuhn L, Cotton M, Giaquinto C, Rossi P, Rensburg JVA, Violari A, Lain GM, Lopez-Varela E, Sylla M, Amugue P, Rojo P, Tagarro A for EPIICAL Consortium

Presented at: CROI 2024

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The development of the Belgian paediatric clinical trial network

2024

Authors: Degraeuwe E, Persijn L, Nuytinck L, Allegaert K, De Taeye L, Gasthuys E, Christiaens D, Karamaria S, Raes A, Turner M, Vande Walle J. 

Published in: Acta Clinica Belgica

Psychopharmacology in children and adolescents: unmet needs and opportunities

2024

Authors: Cortese S, Purper-Ouakil D, Apter A, Arango C, Baeza I, Banaschewski T, Buitelaar J, Castro-Fornieles J, Coghill D, Cohen D, Correll CU, Grünblatt E, Hoekstra PJ, James A, Jeppesen P, Nagy P, Pagsberg AK, Parellada M, Persico AM, Roessner V, Santosh P, Simonoff E, Stevanovic D, Stringaris A, Vitiello B, Walitza S, Weizman A, Wong ICK, Zalsman G, Zuddas A, Carucci S, Butlen-Ducuing F, Tome M, Bea M, Getin C, Hovén N, Konradsson-Geuken A, Lamirell D, Olisa N, Nafria Escalera B, Moreno C.

Published in: Lancet Psychiatry

Major revision version 12.0 of the European AIDS Clinical Society guidelines 2023

2024

Authors: Ambrosioni J, Levi L, Alagaratnam J, Van Bremen K, Mastrangelo A, Waalewijn H, Molina JM, Guaraldi G, Winston A, Boesecke C, Cinque P, Bamford A, Calmy A, Marzolini C, Martínez E, Oprea C, Welch S, Koval A, Mendao L, Rockstroh JK; EACS Governing Board.

Published in: HIV Medicine

Core Outcome Measurement Set for Research and Clinical Practice in Post COVID-19 Condition (Long COVID) in Children and Young People: An International Delphi Consensus Study “PC-COS Children”

2024

Authors: Seylanova N, Chernyavskaya A, Degtyareva N, Mursalova A, Ajam A, Xiao L, Aktulaeva K, Roshchin P, Bobkova P, Aiyegbusi OL, Anbu AT, Apfelbacher C, Asadi-Pooya AA, Ashkenazi-Hoffnung L, Brackel C, Buonsenso D, de Groote W, Diaz JV, Donà D, …, Thorne C, Vijverberg S, Warner JO, Were WM, Williamson PR, Munblit D.

Published in: European Respiratory Journal

Age-specific transmission dynamics of SARS-CoV-2 during the first two years of the pandemic

2024

Authors: Boldea O, Alipoor A, Pei S, Shaman J, Rozhnova G.

Published in: PNAS Nexus

How does post COVID differ from other post-viral conditions in childhood and adolescence (0–20 years old)? A systematic review

2024

Authors: Minotti C, McKenzie C, Dewandel I, Bekker C, Sturniolo G, Doni D, Giaquinto C, Van Der Zalm MM, Donà D.

Published in: eClinical Medicine

Prophylactic Intravenous Acetaminophen in Extremely Premature Infants: Minimum Effective Dose Research by Bayesian Approach

2024

Authors: Bouazza N, Cambonie G, Flamant C, Rideau A, Tauzin M, Patkai J, Gascoin G, Lumia M, Aikio O, Lui G, Bournaud LF, Walsh-Papageorgiou A, Tortigue M, Baruteau AE, Kallio J, Hallman M, Diallo A, Levoyer L, Treluyer JM, Roze JC. 

Published in: Paediatric Drugs

Epidemic graph diagrams as analytics for epidemic control in the data-rich era

2024

Authors: Valdano E, Colombi D, Poletto C, Colizza V.

Published in: Nature Communications

Clinical spectrum of disease and outcomes in children with Omicron SARS-COV-2 infection in Cape Town, South Africa

2024

Authors: Bekker C, Dewandel I, Redfern A, McKenzie C, Lishman J, Verhagen LM, Claassen M, Wilson S, Dunbar R, Bosch C, van Zyl G, Preiser W, Goussard P, Rabie H, van der Zalm MM.

Published in: IJTLD OPEN

Development and performance of the c4c national clinical trial networks for optimizing pediatric trial facilitation

2023

Authors: Degraeuwe E, van der Geest T, Persijn L, Nuytinck L, Raes A, Turner M, Fernandes RM, Vande Walle J, de Wildt SN; IMI2 project conect4children (c4c) consortium, including National Hubs/Networks Belgian Pediatric Clinical Research Network (BPCRN) (Belgium) and Pedmed-NL (Netherlands).

Published in: Frontiers in Pediatrics

Changing character and waning impact of COVID-19 at a tertiary centre in Cape Town, South Africa

2023

Authors: Hermans LE, Booysen P, Boloko L, Adriaanse M, de Wet TJ, Lifson AR, Wadee N, Papavarnavas N, Marais G, Hsiao NY, Rosslee MJ, Symons G, Calligaro GL, Iranzadeh A, Wilkinson RJ, Ntusi NAB, Williamson C, Davies MA, Meintjes G, Wasserman S.

Published in: Southern African journal of infectious diseases

Simultaneous pharmacokinetic modeling of unbound and total darunavir with ritonavir in adolescents: a substudy of the SMILE trial

2023

Authors: Abdalla S, Compagnucci A, Riault Y, Chan KM, Bamford A, Nolan A, Ramos TJ, Constant V, Nguyen T, Zheng Y, Tréluyer J, Froelicher-Bournaud L, Neveux N, Saidi Y, Cressey RT, Hirt D on behalf of the SMILE study group

Published in: Antimicrobial Agents and Chemotherapy

Stronger and durable SARS-CoV-2 immune response to mRNA vaccines in 5–11 years old children with prior COVID-19

2023

Authors: Di Chiara C, Cantarutti A, Petrara MR, Bonfante F, Benetti E, Boracchini R, Bosa L, Carmona F, Cosma C, Cotugno N, Le Prevost M, Martini G, Meneghel A, Pagliari M, Palma P, Ruffoni E, Zin A, De Rossi A, Giaquinto C, Donà D, Padoan A.

Published in: Vaccine

Longevity of mucosal and systemic SARS-CoV-2 antibodies in South African vs Dutch children with respiratory tract infections

2023

Authors: van Weelden G, Dewandel I, de Jonge MI, Redfern A, Bekker C, Lochan H, van der Gaast C, Van Niekerk M, Mentor M, Mfazwe A, Fröberg J, Diavatopoulos D, Donà D, Rabie H, van der Zalm M, Verhagen LM.

Presented at: International Congress of Immunology (IUIS)

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Navigating the COVID-19 Pandemic for Participant Recruitment and Follow-up: Experiences from the PediCAP Clinical Trial Consortium

2023

Authors: Kiggwe A, Nalwanga D, Tagoola A, Madhi S, Moore PD, Archary M, Mulenga V, Mujuru AH, Sacarlal J, Buck WC, Sidat M, Nguyen H, Haque F, Dennis E, Clements M, Murphy B, Spittle B, Viero F, Bielicki J, Musiime V,  Sharland M

Presented at: The EDCTP Forum 2023

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External factors affecting recruitment in a global paediatric pneumonia trial: lessons learned from PediCAP

2023

Authors: Pillay K, Archary M, Bielicki J, Buck WC, Clements M, Dennis E, Goelen J, Haque F, Kiggwe A, Madhi S, Moore PD, Mujuru AH, Mulenga V, Murphy B, Musiime V, Nalwanga D, Nguyen H, Sacarlal J, Sidat M, Spittle B, Tagoola A, Viero F, Sharland M

Presented at: The EDCTP Forum 2023

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Building a national network for inpatient pediatric clinical research in Mozambique 

2023

Authors: Sacarlal WJ, Buck C, Passanduca A, Macassa E, Saíde A, Chhaganlal K, Gafur M, Seni A, Machava S, Martins L, Issa F, Macanze E, Manjate N, Chaúque S, Langa S, Sidat M, Cassia U, Salimo A, Mavume C, Massitela C, Maieca A, Joaquim W, Martins S, Adriano Q, Zandamela M, Bramugy J, Bassat Q, Moraleda C, Tagarro A, Sharland M, Rojo P

Presented at: The EDCTP Forum 2023

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Receipt of intravenous co-amoxiclav challenged eligibility screening for the PediCAP Trial in Johannesburg, South Africa 

2023

Authors: Moore PD, Waggie Z, Nkosi S, Nkosi L, Kumalo N, Nkumana N, Zulu N, Dangor Z, Sharland M, Madhi S

Presented at: The EDCTP Forum 2023

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‘Nothing about us without us’: Multi-country adolescent patient-led recruitment information in the Long-Acting Treatment in Adolescents(LATA) trial – an animated video to compliment ‘traditional’ participant information  

2023

Authors: Conway M, Jafta L, Shibemba M, South A, Kityo Mutuluuza C, Bwakura-Dangarembizi M, Siika A, Archary M, Akabwai GP, Resty Babirye Okello, Mugerwa H, Nathoo K, Mujuru H, Chidziva E, Bhiri J, Nyandiko W, Kirui V, Kiilu C, Mosia R, Mngqbisa R, Ngwenya N, Seunanden T, Namukway S, Seeley J, Thomason M, Bush M, Dodds B, Ford D, Apoto N, Pett SL, Kekitiinwa-Rukyalekere A on behalf of the BREATHER Plus Consortium 

Presented at: The EDCTP Forum 2023

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