Publications

Descriptive interim analysis of the sampling strategy in anonymous repeated cross-sectional samples in European neonatal intensive care units (NICU)

2023

Authors: Golhen K, Gotta V, Pfister M, Bielicki J.

Presented at: ESPID 2023

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The impact of variant and vaccination on SARS-CoV-2 symptomatology; three prospective household cohorts

2023

Authors: Westerhof I, de Hoog M, Ieven M, Lammens C, van Beek J, Rozhnova G, Eggink D, Euser S, Wildenbeest J, Duijts L, van Houten M, Goossens H, Giaquinto C, Bruijning‑Verhagen P.

Presented at: ESPID 2023

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Ethnic group differences in rates of SARS-CoV-2 testing, PCR-confirmed infections and COVID-19 related hospital admissions in young children by SARS-CoV-2- variant: national birth cohort study

2023

Authors: Abdullahi F, Hardelid P, Nguyen V, Thorne C, Linda Wijlaar.

Presented at: ESPID 2023

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Clinical presentation and outcome of acute respiratory illnesses in South African children during the COVID-19 pandemic

2023

Authors: Redfern A, van der Zalm MM, Lishman J, Goussard P, Smit L, Dagan R, Barday MM, Mare M, Claassen M, Van Zyl G, Rabie H, Verhagen LM.

Presented at: ESPID 2023

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Clinical features of SARS-CoV-2 infection in children and adolescents who experienced COVID-19 across Parental, Delta, and Omicron waves in Italy: a prospective observational study

2023

Authors: Di Chiara C, Boracchini R, Sturniolo G, Barbieri A, Costenaro P, De Pieri M, Liberati C, Zin A, Cozzani S, Padoan A, Bonfante F, Kakkar F, Cantarutti A, Donà D, Giaquinto C.

Presented at: ESPID 2023

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Hybrid immunity upon mRNA vaccines induce a stronger and durable SARS-CoV-2 immune response in children

2023

Authors: Di Chiara C, Cantarutti A, Petrara MR, Bonfante F, Cosma C, Carmona F, Pagliari M, Cotugno N, Boracchini R, Meneghel A, Benetti E, Bosa L, Palma P, De Rossi A, Giaquinto C, Donà D, Padoan A, and the VERDI/ORCHESTRA study teams.

Presented at: ESPID 2023

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Optimizing the World Health Organization algorithm for HIV vertical transmission risk assessment by adding maternal self-reported antiretroviral therapy adherence

2023

Authors: Fernández-Luis S, Lain MG, Serna-Pascual M, Domínguez-Rodríguez S, Kuhn L, Liberty A, Barnabas S, Lopez-Varela E, Otwombe K, Danaviah S, Nastouli E, Palma P, Cotugno N, Spyer M, Giannuzzi V, Giaquinto C, Violari A, Cotton MF, Nhampossa T, Klein N, Ramsagar N, van Rensburg AJ, Behuhuma O, Vaz P, Maiga AI, Oletto A, Naniche D, Rossi P, Rojo P, Tagarro A; EPIICAL Consortium

Published in: BioMed Central

Determinants of B-Cell Compartment Hyperactivation in European Adolescents Living With Perinatally Acquired HIV-1 After Over 10 Years of Suppressive Therapy

2023

Authors: Ruggiero A, Pascucci GR, Cotugno N, Domínguez-Rodríguez S, Rinaldi S, Tagarro A, Rojo P, Foster C, Bamford A, De Rossi A, Nastouli E, Klein N, Morrocchi E, Fatou B, Smolen KK, Ozonoff A, Di Pastena M, Luzuriaga K, Steen H, Giaquinto C, Goulder P, Rossi P, Levy O, Pahwa S, Palma P; EPIICAL Consortium

Published in: Frontiers

Machine learning outperformed logistic regression classification even with limit sample size: A model to predict pediatric HIV mortality and clinical progression to AIDS

2023

Authors: Domínguez-Rodríguez S, Serna-Pascual M, Oletto A, Barnabas S, Zuidewind P, Dobbels E, Danaviah S, Behuhuma O, Lain MG, Vaz P, Fernández-Luis S, Nhampossa T, Lopez-Varela E, Otwombe K, Liberty A, Violari A, Maiga AI, Rossi P, Giaquinto C, Kuhn L, Rojo P, Tagarro A; EPIICAL Consortium

Published in: Plos One

Clinical, Virological and Immunological Subphenotypes in a Cohort of Early Treated HIV-Infected Children

2023

Authors: Domínguez-Rodríguez S, Tagarro A, Foster C, Palma P, Cotugno N, Zicari S, Ruggiero A, de Rossi A, Dalzini A, Pahwa S, Rinaldi S, Nastouli E, Marcelin AG, Dorgham K, Sauce D, Gartner K, Rossi P, Giaquinto C, Rojo P

Published in: Frontiers

Multifaceted premature aging in adolescent/young adult with perinatal acquired HIV

2023

Authors: Petrara MR, Ruffoni E, Carmona F, Cavallari I, Zampieri S, Giunco S, Bianco Del P, Rampon O, Palma P, Rossi P, Giaquinto C, Rossi De A, within the EPIICAL Consortium

Presented at: CROI 2023

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Participatory Surveillance for COVID-19 Trend Detection in Brazil: Cross-sectional Study

2023

Authors: Wittwer S, Paolotti D, Lichand G, Leal Neto O.

Published in: JMIR Public Health and Surveillance

Implementation of a centralized pharmacovigilance system in academic pan-European clinical trials: Experience from EU-Response and conect4children consortia

2023

Authors: Terzić V, Levoyer L, Figarella M, Bigagli E, Mercier N, De Gastines L, Gibowski S, Trøseid M, Demotes J, Olsen IC, Hites M, Ader F, Lopez JRA, Mentré F, Espérou H, Costagliola D, Røttingen JA, Poissy J, Rozé JC, Warris A, O’Leary J, Fernandes RM, Assoumou L, Hankard R, Turner MA, Yazdanpanah Y, Diallo A; EU-Response safety group; c4c safety group.

Published in: British Journal of Clinical Pharmacology

Time for a new CoNSensus? Species specificity of coagulase negative staphylococci (CoNS) antibiograms in neonatal bloodstream isolates across Europe

2023

Authors: Hill LF, Planche T, Monahan I, Gupta A, Turner MA, Lutsar I, Roilides E, Clements MN, Sharland M, Heath PT, Lindsay JA, on behalf of the NeoVanc Consortium

Presented at: ECCMID 2023

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Infection prevention and control practices in neonatal units participating in the NeoIPC project

2023

Authors: Schlaeppi C, Bielicki J, and the NeoIPC Consortium

Presented at: ECCMID 2023

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Antibiotic use in neonatal care: measuring cumulative exposure in point prevalence surveys identifies high infant-level antibiotic exposure

2023

Authors: Cook A, Bielicki J, and the NeoIPC Consortium

Presented at: ECCMID 2023

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The Mini-Symposium on Global Child Health: Serving the Children of the World

2023

Authors: Scutariu C, Bilardi D, Ayomoh F.I. et al. 

Published in: Pediatric Research

Clinical, methodology, and patient/carer expert advice in pediatric drug development by conect4children

2023

Authors: Cheng K, Mahler F, Lutsar I, Nafria Escalera B, Breitenstein S, Vassal G, Claverol J, Noel Palacio N, Portman R, Pope G, Bakker M, van der Geest T, Turner MA, de Wildt SN; c4c Expert Group Leads.

Published in: Clinical and Translational Science

Paediatric Inflammatory Bowel Disease: A Multi-Stakeholder Perspective to Improve Development of Drugs for Children and Adolescents

2023

Authors: Croft NM, de Ridder L, Griffiths AM, Hyams JS, Ruemmele FM, Turner D, Cheng K, Lutsar I, Greco M, Gołębiewska Z, Laumond F, Cavaller-Bellaubi M, Elgreey A, Altepeter TA, Pallidis C, Norga K, Nelson R, Crandall W, Vassal G.

Published in: Journal of Crohns and Colitis

Youth Participation in Clinical Trials and Research

2023

Author: Mercy Shibemba

Presented at: CHIVA 2023

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Dengue, chikungunya and zika arbovirus infections in Caribbean children

2023

Authors: CDC Christie, AM Lue, RH Melbourne-Chambers

Presented at: Current Opinion in Pediatrics

Mortality linked to higher inflammation in kids with perinatal HIV

2023

Speaker: Morrocchi E

Presented at: CROI 2023

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Outcomes of laboratory-confirmed SARS-CoV-2 infection during resurgence driven by Omicron lineages BA.4 and BA.5 compared with previous waves in the Western Cape Province, South Africa

2023

Authors: Davies MA, Morden E, Rousseau P, Arendse J, Bam JL, Boloko L, Cloete K, Cohen C, Chetty N, Dane P, Heekes A, Hsiao NY, Hunter M, Hussey H, Jacobs T, Jassat W, Kariem S, Kassanjee R, Laenen I, Roux SL, Lessells R, Mahomed H, Maughan D, Meintjes G, Mendelson M, Mnguni A, Moodley M, Murie K, Naude J, Ntusi NAB, Paleker M, Parker A, Pienaar D, Preiser W, Prozesky H, Raubenheimer P, Rossouw L, Schrueder N, Smith B, Smith M, Solomon W, Symons G, Taljaard J, Wasserman S, Wilkinson RJ, Wolmarans M, Wolter N, Boulle A.

Published in: International Journal of Infectious Diseases

mRNA vaccines induce a higher antibodies response in children with previous COVID-19

2023

Authors: Di Chiara C, Cantarutti A, Bonfante F, Petrara MR, Cosma C, Pagliari M, Cotugno N, Meneghel A, Benetti E, Bosa L, Palma P, De Rossi A, Giaquinto C, Donà D, Padoan A, for the VERDI study team.

Presented at: CROI 2023

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Management of Mpox in people with HIV attending a sexual health department in London, UK

2023

Authors: Girometti N, Burton F, Spencer M, Agunbiade S, Byrne R, Bracchi M, Jones R, Dwyer E, Whitlock GG, Tittle V, Pozniak AL, Boffito M

Presented at: CROI 2023

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SARS-COV-2 in children & adolescents living with HIV in Europe & South Africa

2023

Authors: Jackson C, Crichton S, Bamford A, Berzosa A, Gilmour K, Goetghebuer T,  Johnson SM, Judd A, Noguera-Julian A, Le Prevost M, Spoulou V, Sturgeon K,  VolokhamA, Zar HJ, Collins IJ. On behalf of the European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC)

Presented at: CROI 2023

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Persistent symptoms in children admitted with COVID similar to controls 1 year later

2023

Authors: Tagarro A, Villanueva S, Esteban A, López M, Conde M, de Pablo L, Aguilera-Alonso D, Gastesi I, Domínguez S, Epalza C, Ballesteros A, Pinto C, Giaquinto C, Moraleda C, on behalf of EPICO and ORCHESTRA Working Group

Presented at: CROI 2023

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Comorbidities that increase risk for severe acute COVID-19 in pediatric population

2023

Authors: García TA, García GI, Medina VS, Varela RA, Rubio MLM, Hoyos VP, Friedrich G, Vanegas NM, Gualteros RS, Vaquero LO, Mejía ML, Álvarez C, Gordillo LI, Rey CC, Errondo EC, Arandes ST, Ruiz MA, Gómez NM, Aguirre HM, Pérez FV, le Prevost M, Giaquinto C, Redecilla MC

Presented at: CROI 2023

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Pediatric coronavirus disease 2019 in Africa

2023

Authors: Van der Zalm MM, Donà D, Rabie H.

Published in: Current Opinions in Pediatrics

Standardizing Paediatric Clinical Data: The Development of the conect4children (c4c) Cross Cutting Paediatric Data Dictionary

2023

Authors: Sen A, Hedley V, Owen J, Cornet R, Kalra D, Engel C, Palmeri A, Lee J, Roze J, Standing JF, Warris A, Pansieri C, Leary R, Turner M, Straub V.

Published in: Journal of the Society for Clinical Data Management

Perinatal characteristics and longer-term outcomes in Brazilian children with confirmed or suspected congenital Zika infection: ZIKAction Paediatric Registry

2023

Authors: de Siquiera I.C, de Almeida B.L, Lage MLC, Serra L, Carvalho A, de Lima M.M, Góes MDFN, Crispim MDSIN, da Costa Pereira MM, Costa BGG, Bailey H, Byrne T, Giaquinto C, Fernandes G, Ruiz-Burga E, & Thorne C

Published in: Dialogues in Health, 2, 100104

Evaluating COVID-19 vaccine allocation policies using Bayesian m-top exploration

2023

Authors: Cimpean A, Verstraeten T, Willem L, Hens N, Nowé A, Libin P.

Published in: medRxiv (preprint), January 2023

Multi-centre, randomised, open-label, blinded endpoint assessed, trial of corticosteroids plus intravenous immunoglobulin (IVIG) and aspirin, versus IVIG and aspirin for prevention of coronary artery aneurysms (CAA) in Kawasaki disease (KD): the KD CAA prevention (KD-CAAP) trial protocol

2023

Authors: Eleftheriou D, Moraes YC, Purvis C, Pursell M, Morillas MM, Kahn R, Mossberg M, Kucera F, Tulloh R, Standing JF, Swallow V, McCormack R, Herberg J, Levin M, Wan M, Klein N, Connon R, Walker AS, Brogan P.

Published in: Trials

Mid- and Long-Term Atrio-Ventricular Functional Changes in Children after Recovery from COVID-19

2023

Authors: Sabatino J, Di Chiara C, Di Candia A, Sirico D, Donà D, Fumanelli J, Basso A, Pogacnik P, Cuppini E, Romano LR, Castaldi B, Reffo E, Cerutti A, Biffanti R, Cozzani S, Giaquinto C, Di Salvo G.

Published in: Journal of Clinical Medicine

Early Treatments of Fragile Children with COVID-19—Results of CLEVER (Children COVID Early Treatment), a Retrospective, Observational Study

2023

Authors: Minotti C, Mengato D, De Pieri M, Trivellato S, Francavilla A, Di Chiara C, Liberati C, Mattera R, Biffi A, Giaquinto C, Venturini F, Donà D.

Published in: Viruses

Attitudes towards booster, testing and isolation, and their impact on COVID-19 response in winter 2022/2023 in France, Belgium, and Italy: a cross-sectional survey and modelling study

2023

Authors: De Meijere G, Valdano E, Castellano C, Debin M, Kengne-Kuetche C, Turbelin C, Noël H, Weitz J, Paolotti D, Hermans L, Hens N, Colizza V.

Published in: The Lancet Regional Health – Europe

General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children

2022

Authors: Bouazza N, Dokoumetzidis A, Knibbe CAJ, de Wildt SN, Ambery C, De Cock PA, Gasthuys E, Foissac F, Urien S, Hamberg AK, Poggesi I, Zhao W, Vermeulen A, Standing JF, Tréluyer JM; c4c Expert group on Pharmacometrics

Published in: British Journal of Clinical Pharmacology

Health technology assessment of paediatric medicines: European landscape, challenges and opportunities inside the conect4children project

2022

Authors: Moretti F, Ruiz F, Bonifazi F, Pizzo E, Kindblom JM; c4c HTA expert group.

Published in: British Journal of Clinical Pharmacology

Path towards efficient paediatric formulation development based on partnering with clinical pharmacologists and clinicians, a conect4children expert group white paper

2022

Authors: Walsh J, Schaufelberger D, Iurian S, Klein S, Batchelor H, Turner R, Gizurarson S, Boltri L, Alessandrini E, Tuleu C.

Published in: British Journal of Clinical Pharmacology

c4c: Paediatric pharmacovigilance: Methodological considerations in research and development of medicines for children – A c4c expert group white paper

2022

Authors: Aurich B, Apele-Freimane D, Banaschewski T, Chouchana L, Day S, Kaguelidou F, Kelly LE, Kindblom JM, Neubert A, Wong ICK.

Published in: British Journal of Clinical Pharmacology

Current knowledge, challenges and innovations in developmental pharmacology: A combined conect4children Expert Group and European Society for Developmental, Perinatal and Paediatric Pharmacology White Paper

2022

Authors: Smits A, Annaert P, Cavallaro G, De Cock PAJG, de Wildt SN, Kindblom JM, Lagler FB, Moreno C, Pokorna P, Schreuder MF, Standing JF, Turner MA, Vitiello B, Zhao W, Weingberg AM, Willmann R, van den Anker J, Allegaert K.

Published in: British Journal of Clinical Pharmacology

The impact of variant and vaccination on SARS-CoV-2 symptomatology; three prospective household cohorts

2022

Authors: Westerhof I, de Hoog M, Ieven M, Lammens C, van Beek J, Rozhnova G, Eggink D, Euser S, Wildenbeest J, Duijts L, van Houten M, Goossens H, Giaquinto C, Bruijning-Verhagen P.

Published in: International Journal of Infectious Diseases

Implementation of infection prevention and control for hospitalised neonates: A narrative review

2022

Authors: Nyantakyi E, Caci L, Castro M, Schlaeppi C, Cook A, Albers B, Walder J, Metsvaht T, Bielicki J, Dramowski A, Schultes MT, Clack L

Published in: Clinical Microbiology and Infection

Understanding paediatric data standards challenges through academia-industry partnerships: A conect4children (c4c) qualitative study

2022

Authors: Sen A, Palmeri A, Lee J, Hedley V, Thuet J, Lignon P, Cotonnec V, Leary R, Nally S, Straub V.

Published in: International Journal of Health Planning and Management

Antibiotics needed to treat multidrug-resistant infections in neonates

2022

Authors: CM Williams PCM, Qazi SA, Agarwal R, Velaphi S, Bielicki JA, Nambiar S, Giaquinto C, Bradley J, Noel GJ, Ellis S, O’Brien S, Balasegaram M & Sharland M

Published in: Bulletin of the World Health Organization

COVID-19 in Infants Less than 3 Months: Severe or Not Severe Disease?

2022

Authors: Donà D, Montagnani C, Di Chiara C, Venturini E, Galli L, Lo Vecchio A, Denina M, Olivini N, Bruzzese E, Campana A, Giacchero R, Salvini F, Meini A, Ponzoni M, Trapani S, Rossi E, Lombardi MH, Badolato R, Pierri L, Pruccoli G, Rossin S, Colomba C, Cazzato S, Pacati I, Nicolini G, Pierantoni L, Bianchini S, Krzysztofiak A, Garazzino S, Giaquinto C, Castelli Gattinara G

Published in: Viruses

Empowering adolescents living with HIV to effectively engage and participate in the development and delivery of clinical trials: A digital model during COVID. 

2022

Authors: ALHIV, Jafta, L; Conway, M; Shibemba, M; Ahimbisibwe, G; Bhiri, J; Carter, A; Cebekhulu, S; Ely, A; Gondo, S; Kiganda, C; Nkosi, N.

Presented at: International Workshop on HIV & Adolescence 2022

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The Development of Quality Standards for the ethical and meaningful participation of children and young people in clinical trials and research

2022

Authors: Burke, T; Conway, M

Presented at: AIDS 2022 an the International Workshop on HIV & Adolescence 2022

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Adolescents living with HIV from multiple countries being lead-partners in the co-production of research information and findings across global clinical trials

2022

Authors: Cebekhulu, S; Shibemba, M; Conway, M; Kiganda, C; Ahimbisibwe, Bhiri, J; Carter, A; Ely, A; Gondo, S; Nkosi, N.

Presented at: AIDS 2022 and International Workshop on HIV & Adolescence 2022

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Health Equity in Pediatric Drug Development: Translating Aspiration into Operation

2022

Authors: Folayan MO, Conway M, Russo C, Diniz N, Jafta LP, Sam-Agudu NA, Bernays S, Santana VM, Epps C, Turner MA

Published in: Springer

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